Evidence map›Paper›PMID 40224412›Full record

ArticleACS omega2025

Synthesis and Characterization of a Novel All-in-One Graphene Oxide-Nafion Polymer Bioconjugate for Application in Electrochemical Biosensing of the

Nang Noon Shean Aye, Pornsuda Maraming, Patcharaporn Tippayawat, Sakda Daduang, Anchalee Techasen, Paiboon Sithithaworn, Roengrut Rujanakraikarn, Nichada Jearanaikoon, Rungrueang Phatthanakun, Ratchadaporn Supruangnet and 2 more

Abstract read
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Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nang Noon Shean AyeBiomedical Sciences Program, Graduate School, Khon Kaen University, Khon Kaen 40002, Thailand.
Pornsuda MaramingCentre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Patcharaporn TippayawatCentre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID https://orcid.org/0000-0002-4452-1284
Sakda DaduangDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Anchalee TechasenCentre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Paiboon SithithawornCholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand.
Roengrut RujanakraikarnSynchrotron Light Research Institute (Public Organization), Nakhon Ratchasima 30000, Thailand.
Nichada JearanaikoonSynchrotron Light Research Institute (Public Organization), Nakhon Ratchasima 30000, Thailand.
Rungrueang PhatthanakunSynchrotron Light Research Institute (Public Organization), Nakhon Ratchasima 30000, Thailand.
Ratchadaporn SupruangnetSynchrotron Light Research Institute (Public Organization), Nakhon Ratchasima 30000, Thailand.
Pat PhotongkamSynchrotron Light Research Institute (Public Organization), Nakhon Ratchasima 30000, Thailand.ORCID https://orcid.org/0000-0002-0645-2126
Jureerut DaduangCentre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID https://orcid.org/0009-0009-5088-811X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioconjugates in electrochemical biosensors can significantly enhance the detection process and sensitivity. In this study, we synthesized a monoclonal antibody-conjugated nanocomposite of graphene oxide and Nafion (GO-Nf-mAb) for application in an electrochemical biosensor as a novel all-in-one bioreceptor. The incorporation of Nafion (Nf) improved the stability, dispersity, and antibody immobilization on the GO surface, thereby increasing the sensitivity of the biosensor. The impact of Nafion on GO stability and antibody conjugation was thoroughly investigated and compared to that of Nafion-free conjugation via various characterization techniques, including X-ray photoelectron spectroscopy (XPS) and synchrotron radiation near-edge X-ray absorption fine structure. The presence of Nafion during monoclonal antibody (mAb) conjugation resulted in an increased peak intensity of the NH

Identifiers

PMID40224412
PMCPMC11983171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.