Evidence map›Paper›PMID 40224270›Full record

ArticleResearch and practice in thrombosis and haemostasis2025

Lower early mortality and risk prediction improvement of obesity after acute pulmonary embolism: results from a multicenter cohort analysis with external validation.

Romain Chopard, Laurent Bertoletti, Marc Badoz, Nicolas Meneveau, Fiona Ecarnot, Luciano López Jiménez, Olga Madridano, José Antonio Díaz Peromingo, Meritxell López De la Fuente, Manuel Monreal and 2 more

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Article in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Romain ChopardDepartment of Cardiology, University Hospital Besançon, Besançon, France.
Laurent BertolettiF-CRIN, INNOVTE network, France.
Marc BadozDepartment of Cardiology, University Hospital Besançon, Besançon, France.
Nicolas MeneveauDepartment of Cardiology, University Hospital Besançon, Besançon, France.
Fiona EcarnotDepartment of Cardiology, University Hospital Besançon, Besançon, France.
Luciano López JiménezInternal Medicine Department, Hospital Universitario Reina Sofía, Córdoba, Spain.
Olga MadridanoDepartment of Internal Medicine, Hospital Infanta Sofía, Madrid, Spain.
José Antonio Díaz PeromingoDepartment of Internal Medicine, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
Meritxell López De la FuenteHospital Universitari Mútua de Terrassa, Terrassa, Cataluña, Spain.
Manuel MonrealCátedra de Enfermedad Tromboembólica, Universidad Católica de Murcia, Murcia, Spain.
Gregory PiazzaDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
RIETE Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between obesity (defined as body mass index [BMI] ≥ 30 kg/m Objectives: We aimed to compare outcomes after pulmonary embolism (PE) between patients with obesity and nonobese, nonunderweight patients. Methods: Using a multicenter registry of prospectively recorded individual patient data, we compared outcome rates using multivariable logistic or Cox regression for 30-day and 6-month outcomes respectively (etiologic analysis). We assessed the incremental value of adding BMI information on top of the 30-day European Society of Cardiology (ESC) prognostic algorithm (prognostic analysis). Results: We included 2390 patients with BMI of ≥18.5 kg/m Conclusion: We present evidence indicating lower early- and mid-term mortality after PE in patients classified as obese based on BMI, compared with nonobese, nonunderweight patients. BMI should likely be incorporated into algorithms or scoring systems for predicting early mortality following PE.

Indexed as

obesityoutcomespulmonary embolism

Identifiers

PMID40224270
PMCPMC11992428

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