Evidence map›Paper›PMID 40224257›Full record

ArticleHeart rhythm O22025

Trends in health care expenditures and incremental health care cost in adults with atrial fibrillation in the United States.

Frans Serpa, Archana Tale, Peter J Zimetbaum, Daniel B Kramer

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. NovelBiomedicines · 2026
    Article
  2. Rare TruncatingGenes · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Frans SerpaRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Archana TaleRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Peter J ZimetbaumRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Daniel B KramerRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is associated with increased health care costs; however, comprehensive data on the financial burden of AF remain limited. Objective: The purpose of this study was to delineate health care expenditures among patients with AF. Methods: We used the longitudinal panels from the Medical Expenditure Panel Survey covering 2016-2019 to estimate health care expenditures associated with AF. We identified individuals 18 years and older with AF in the first year of each panel (2016-2018) by using the Results: The weighted study population included 3,080,055 adults with AF (382 respondents; mean age 71.5; 89.9% white). The adjusted annual total health care cost in adults with AF totaled $14,083 (95% confidence interval $10,887-$17,279) compared with $8771 (95% confidence interval $8106-$9436) for those without AF. The primary drivers of cost over time were hospital inpatient care, office-based visits, and prescribed medications. The annual incremental total health care cost associated with AF was $5312 per adult (in 2019 U.S. dollars). Conclusion: Adults with AF in the United States face a higher financial burden across various health care services than do those without the condition, with consistently increasing expenses in inpatient care and prescribed medicines. Further research is needed to identify the independent contribution of AF to these costs.

Indexed as

Atrial fibrillationFinancial burdenHealth care expenditureMedical expenditureMedical Expenditure Panel Survey

Identifiers

PMID40224257
PMCPMC11993679

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.