Evidence map›Paper›PMID 40224184›Full record

ReviewFrontiers in oncology2025

BRCA1 and BRCA2 as prognostic markers in oral squamous cell carcinoma: a minireview.

Dominika Gedeonová, Claretta Bianchi, Jan Štembírek, Matouš Hrdinka, Zuzana Chyra, Marcela Buchtová, Pavel Hurník, Tomáš Blažek, Jana Režnarová

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Hemidesmosomal Proteins in Oral Cancer Progression: An Immunohistochemical Study of Human and Mouse.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominika GedeonováDepartment of Oral and Maxillofacial Surgery, University Hospital Ostrava, Ostrava, Czechia.
Claretta BianchiDepartment of Oral and Maxillofacial Surgery, University Hospital Ostrava, Ostrava, Czechia.
Jan ŠtembírekDepartment of Oral and Maxillofacial Surgery, University Hospital Ostrava, Ostrava, Czechia.
Matouš HrdinkaDepartment of Oral and Maxillofacial Surgery, University Hospital Ostrava, Ostrava, Czechia.
Zuzana ChyraDepartment of Hematooncology, University Hospital Ostrava, Ostrava, Czechia.
Marcela BuchtováInstitute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czechia.
Pavel HurníkInstitute of Molecular and Clinical Pathology and Medical Genetics, University Hospital Ostrava, Ostrava, Czechia.
Tomáš BlažekClinic of Oncology, University Hospital Ostrava, Ostrava, Czechia.
Jana RežnarováDepartment of Oral and Maxillofacial Surgery, University Hospital Ostrava, Ostrava, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC), a subset of head and neck cancers, primarily originates in the epithelial tissues of the oral cavity. Despite advancements in treatment, the mortality rate for OSCC remains around 50%, underscoring the urgent need for improved prognostic markers. This review explores the role of the

Indexed as

BRCA1BRCA2gene alterationHNSCC (head and neck squamous cell carcinoma)OSCC (oral squamous cell carcinoma)

Identifiers

PMID40224184
PMCPMC11986421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.