Evidence map›Paper›PMID 40224120›Full record

ArticleJournal of dental sciences2025

Comparisons of the smear layer removal efficacy of dual-action irrigants and different activation techniques.

Yanyan Chen, Satoshi Watanabe, Phu Yadanar Aung Myint, Sota Mochizuki, Takashi Okiji

Abstract read
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Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanyan ChenDepartment of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Satoshi WatanabeDepartment of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Phu Yadanar Aung MyintDepartment of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Sota MochizukiDepartment of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Takashi OkijiDepartment of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Dual-action root canal irrigants containing disinfectant(s) and chelator(s) are expected to enhance root canal cleaning efficiency. This study aimed to evaluate the effectiveness of these irrigants and different activation techniques on smear layer removal. Materials and methods: Seventy-six extracted human mandibular premolars were root canal-prepared up to an apical size of #40/0.06, grouped and irrigated as follows, and the smear layer on each third of the canal wall was evaluated using scanning electron microscopy. In Experiment 1, syringe irrigation (SI) was carried out using a dual-action irrigant (Triton or SmearOFF) or a combination of 17% ethylenediaminetetraacetic acid (EDTA) and 6% sodium hypochlorite (NaOCl) (n = 12, each). In Experiment 2, Triton was activated by laser-activated irrigation (LAI) with a novel Er:YAG laser equipment (Adverl SH, Morita Manufacturing, Kyoto, Japan), an LAI protocol called shockwave-enhanced emission photoacoustic streaming (SWEEPS), or ultrasonic-activated irrigation (UAI), and irrigated with SI (n = 10, each). Results: In Experiment 1, the Triton group demonstrated significantly better smear layer scores than the EDTA and NaOCl combination group across all canal thirds ( Conclusion: Triton was more effective than the combination of EDTA and NaOCl in removing the smear layer across all root canal thirds. The efficacy of Triton was further enhanced by activation with LAI and SWEEPS.

Indexed as

ErbiumYAG lasersEr-YAG laserRoot canal irrigantsRoot canal therapyScanning electron microscopySmear layer

Identifiers

PMID40224120
PMCPMC11993013

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.