Evidence map›Paper›PMID 40224100›Full record

ArticleJournal of dental sciences2025

Anemia, hematinic deficiencies, and hyperhomocysteinemia in male and female oral lichen planus patients.

Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, Andy Sun, Chun-Pin Chiang

Abstract read
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Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia Yu-Fong ChangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yu-Hsueh WuDepartment of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yi-Pang LeeDepartment of Dentistry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Yi-Ping WangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Andy SunDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chun-Pin ChiangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Our previous study found that 21.9 %, 13.6 %, 7.1 %, 0.3 %, and 14.8 % of 352 oral lichen planus (OLP) patients have anemia, serum iron, vitamin B12, and folic acid deficiencies, and hyperhomocysteinemia, respectively. This study mainly evaluated the anemia, hematinic deficiencies, and hyperhomocysteinemia in 110 male and 478 female OLP patients. Materials and methods: The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, and homocysteine levels in 110 male and 478 female OLP patients were measured and compared with the corresponding levels in 110 male and 478 female healthy control subjects, respectively. Results: We found that 110 male OLP patients had significantly lower mean blood Hb and serum folic acid levels than 110 male healthy control subjects. Moreover, 478 female OLP patients had significantly lower mean blood Hb and serum iron, vitamin B12, and folic acid levels and significantly higher mean serum homocysteine level than 478 female healthy control subjects. In addition, 110 male OLP patients had significantly higher mean blood Hb and serum iron levels, significantly lower mean serum vitamin B12 and folic acid levels, a significantly higher frequency of folic acid deficiency, and significantly lower frequencies of blood Hb and serum iron deficiencies than 478 female OLP patients. Conclusion: The male OLP patients do have significantly higher mean blood Hb and serum iron levels, significantly lower mean serum vitamin B12 and folic acid levels, a significantly higher frequency of folic acid deficiency, and significantly lower frequencies of blood Hb and serum iron deficiencies than female OLP patients.

Indexed as

Folic acidHemoglobinHomocysteineIronOral lichen planusVitamin B12

Identifiers

PMID40224100
PMCPMC11993056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.