ArticleJournal of dental sciences2025
Candidacidal activities of zinc compounds based on incubation time, pH, and ionic strength - An in vitro study.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of topical application of zinc compounds for oral mucosal diseases: A systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Given the antifungal activity of zinc compounds against Materials and methods: Two zinc compounds (zinc chloride and sulfate) and three Results: The candidacidal activities of the zinc compounds significantly increased with increasing incubation time, decreasing pH, and increasing ionic strength. Significant levels of candidacidal activity were detected even within 10 min of incubation. The zinc compounds provided additional candidacidal activity under each pH and ionic strength condition. However, the effects of adding zinc compounds were less than those of lowering pH or increasing ionic strength. The candidacidal activities at each incubation time, pH, and ionic strength varied depending on the zinc compound and Conclusion: The candidacidal activity of the zinc compounds occurred immediately. They provided additional candidacidal activities even at low pH or high ionic strength environments. Oral healthcare products containing zinc compounds can provide antifungal activities in a changing oral environment.
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