ArticleJournal of dental sciences2025
Rapid detection of Lys-gingipain using fluorogenic peptide substrate for diagnosis of periodontitis.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Advanced immunodiagnostics for periodontal disease: Targeted detection of Kgp and RgpB using A7 and G1 antibody set.Journal of advanced research · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Early detection of periodontitis and its associated pathogens has become imperative in oral health. Materials and methods: To confirm the biological activity of the fluorogenic His-Glu-Lys containing peptide substrate which is specific to the Kgp, we compared the fluorescence intensity of the fluorogenic peptide substrate with saliva samples obtained from both healthy individuals (n = 31) and periodontitis patients (n = 30). Results: The results from the fluorogenic substrate were statistically compared with polymerase chain reaction (PCR) results of Conclusion: We anticipate that the fluorogenic peptide substrate will assist in detecting early stages of periodontitis and ultimately prevent further complications. This fluorogenic peptide substrate can be used as a basic material for various types of biosensors.
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