Evidence map›Paper›PMID 40224068›Full record

ArticleJournal of dental sciences2025

Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with iron deficiency.

Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, Andy Sun, Chun-Pin Chiang

Abstract read
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In one paragraph

Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia Yu-Fong ChangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yu-Hsueh WuDepartment of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yi-Pang LeeDepartment of Dentistry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Yi-Ping WangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Andy SunDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chun-Pin ChiangDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Our previous study found that 99 of 588 oral lichen planus (OLP) patients have iron deficiency (ID). This study assessed whether all OLP patients with ID (so-called ID/OLP patients) had iron deficiency anemia (IDA) and evaluated whether the ID/OLP patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects. Materials and methods: The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 99 ID/OLP patients and 588 healthy control subjects were measured and compared. Results: We found that 99 ID/OLP patients had significantly lower mean blood Hb and serum iron, vitamin B12, folic acid levels as well as significantly higher mean serum homocysteine level than 588 healthy control subjects (all Conclusion: ID/OLP patients have significantly higher frequencies of blood Hb and serum vitamin B12 and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity than healthy control subjects. Although the IDA (50.0 %) is the most common type of anemia in our 64 anemic ID/OLP patients, there are still 46.9 % of the 64 anemic ID/OLP patients who had the normocytic anemia.

Indexed as

Gastric parietal cell antibodyHyperhomocysteinemiaIron deficiencyIron deficiency anemiaNormocytic anemiaOral lichen planus

Identifiers

PMID40224068
PMCPMC11993001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.