ArticleJournal of dental sciences2025
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: The adjunctive use of antibiotics in periodontal therapy may lead to resistance and undesired effects, which can be mitigated by alternative agent such as Materials and methods: Fibrin hydrogels were incorporated with various concentrations of LC-EO and the releasing of LC-EO was determined by measuring the wavelength absorbance. Their antibacterial activity was tested against Results: The absorbance wavelength of LC-EO at 230 nm was the optimal wavelength using for the standard curve. The release of 1.0% (v/v) LC-EO from fibrin hydrogel in PBS was 0.03% (v/v) in the first hour and lasted for 24 h. The gradually release of LC-EO was observed until day 30 with the concentration of 0.008% (v/v). The minimum bactericidal concentration against Conclusion: Fibrin hydrogel with LC-EO effectively inhibited bacterial growth in a dose-dependent manner. Cytotoxicity assays also revealed concentration-dependent effects on HGF. Our results suggest the potential use of fibrin hydrogel with LC-EO as a novel adjunctive treatment in periodontal diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.