Evidence map›Paper›PMID 40223708›Full record

ReviewWiley interdisciplinary reviews. RNA

Advances in Detection Methods for A-to-I RNA Editing.

Yuxi Yang, Masayuki Sakurai

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuxi YangResearch Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.ORCID 0009-0004-6650-9026
Masayuki SakuraiResearch Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.ORCID 0000-0002-6920-1746

Funding

Astellas Foundation for Research on Metabolic DisordersJapan Agency for Medical Research and Development JP22ym0126804j0001/21-A-38Japan Agency for Medical Research and Development JP24gm7010005Japan Society for the Promotion of Science 22H02548Japan Society for the Promotion of Science JP18H06054Japan Society for the Promotion of Science JP19H03159Japan Society for the Promotion of Science JP19K16037Takeda Science Foundation
6 · The paper itself

Abstract

Adenosine-to-inosine (A-to-I) RNA editing is a key post-transcriptional modification that influences gene expression and various cellular processes. Advances in sequencing technologies have greatly contributed to the identification of A-to-I editing sites, providing insights into their distribution across coding and non-coding regions. These developments have facilitated the discovery of functionally relevant editing events and have advanced the understanding of their biological roles. This review presents the evolution of methodologies for RNA editing detection and examines recent advances, including chemically-assisted, enzyme-assisted, and quantitative approaches. By evaluating these techniques, we aim to help researchers select the most effective tools for investigating RNA editing and its broader implications in health and disease.

Indexed as

AdenosineInosineRNA EditingAnimalsHumansAdenosineInosineA‐to‐I RNA editingenzyme‐assisted detectioninosine chemical labelinginosine detection

Identifiers

PMID40223708
PMCPMC11995373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.