Evidence map›Paper›PMID 40223638›Full record

ArticleBiotechnology journal2025

Ta-Ag Coatings on TC4: A Strategy to Leverage Bioelectric Microenvironments for Enhanced Antibacterial Activity.

Yuxin Gong, Xiang Liang, Le Bai, Ming Yu, Xin Yang, Chonghao Yao, Hao Cui, Linyang Xie, Bingheng Lu, Sijia Na and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuxin GongKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Xiang LiangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Le BaiKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Ming YuKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Xin YangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Chonghao YaoKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Hao CuiKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Linyang XieKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Bingheng LuState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, China.
Sijia NaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Guangbin ZhaoState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, China.
Junbo TuKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.
Fangfang XuKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi' an Jiaotong University, Xi' an, China.ORCID https://orcid.org/0009-0009-0956-0040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental implant-related infections are serious complications after surgery that can results in loosening or even complete loss of the implant. Although endogenous electric fields (EEF) play an integral role in the human body, current methods involving external electrical stimulation are invasive and not suitable for clinical application. In this study, we using DC magnetron sputtering, investigates the effects of tantalum-silver (Ta-Ag) coatings on titanium alloy (TC4) surfaces, focusing on their potential to influence EEF that enhances antibacterial activity In this design, Ta-Ag configuration effectively increased the surface potential difference of TC4, and furthermore, promoting Ta/Ag ions release and reducing bacterial adhesion. The study concludes that the Ta-Ag coating, particularly the TT/A implant, promotes a stable EEF, enhancing the long-term antibacterial and osteogenic properties of implants. This work provides a promising strategy for developing advanced implant materials with improved clinical efficacy.

Indexed as

Anti-Bacterial AgentsCoated Materials, BiocompatibleSilverTantalumTitaniumAlloysBacterial AdhesionDental ImplantsHumansStaphylococcus aureusSurface PropertiesAlloysAnti-Bacterial AgentsCoated Materials, BiocompatibleDental ImplantsSilverTantalumTitaniumantibacterialcharge transferendogenous electric fieldsosteointegrationTa‐Ag coating

Identifiers

PMID40223638
PMCPMC11995244

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.