ArticleJournal of gynecologic oncology2025
The impact of bladder volume on dosimetric outcomes in VMAT for cervical cancer patients after surgery.
Article in Journal of gynecologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Interfractional variability and reproducibility of accumulated dose in cervical cancer radiotherapy associated with bladder volume.Radiological physics and technology · 2026Article
- Platform-specific comparison of IMRT and VMAT angular resolution for Ethos-based online adaptive radiotherapy in cervical cancer.Frontiers in oncology · 2026Article
- Effect of bladder volume on dose of exposure to dangerous organs and incidence of cystitis and enteritis in patients with cervical cancer after external radiotherapy.Frontiers in oncology · 2026Article
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Authors and funding
3 authors.
Funding
Abstract
objectiveThis study aimed to investigate the impact of bladder volume on dosimetric outcomes of organs at risk (OARs) in postoperative volumetric-modulated arc therapy (VMAT) for patients with cervical cancer.
methodsThe study included 71 cervical cancer patients who received radical hysterectomy and postoperative VMAT between January 2020 and January 2023. Patients were divided into 3 groups according to average bladder volume observed in computed tomography simulation positioning images: Group A (<300 mL), Group B (300-500 mL), and Group C (≥500 mL). The study compared dosimetric parameters(V₃₀, V₄₀, V₄₅, and D
resultsThe median follow-up of the cohort was 33 months, with a median patient age of 48 years. Group A demonstrated the highest V₄₀ and V₄₅ values for the bladder (p<0.05). Conversely, Group C displayed the highest values for the V₄₀ and V₄₅ of the rectum, as well as the V₄₅ and D
conclusionBladder volume significantly affects dosimetry of the bladder, rectum, and sigmoid colon in postoperative VMAT for cervical cancer patients. A recommended bladder volume of 300-500 mL helps reduce radiation-induced cystitis and proctitis.
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