ArticleClinical and experimental otorhinolaryngology2025
Insights Into Responses to Caloric and Head Impulse Stimulation in Lateral Semicircular Canal Benign Paroxysmal Positional Vertigo.
Article in Clinical and experimental otorhinolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesThe aim of this study was to investigate the pathophysiology of persistent geotropic direction-changing positional nystagmus (pGeo DCPN) by analyzing caloric responses and the clinical course in patients with pGeo DCPN and other variants of lateral semicircular canal benign paroxysmal positional vertigo (LSCC BPPV).
methodsIn this prospective case-control study, 101 patients diagnosed with pGeo DCPN (pGeo group, n=34), persistent apogeotropic (pApo) DCPN (pApo group, n=40), or transient geotropic (tGeo) DCPN (tGeo group, n=27) involving the LSCC were enrolled. The video head impulse test (vHIT) and caloric test were performed at diagnosis. If one or both tests were abnormal, follow-up testing was conducted after nystagmus resolution. Differences in test.
resultsand clinical courses among the LSCC BPPV types were analyzed and compared.
resultsThe mean disease duration was significantly longer in patients with pGeo (23.0 days) than those with pApo (8.0 days) and tGeo (9.0 days) (P<0.005). All patients demonstrated normal vHIT gain. The pGeo group showed the highest canal paresis (CP) value (vs. pApo: P=0.002; vs. tGeo: P<0.001) and a higher frequency of abnormal CP (61.8%) than the pApo (22.5%) and tGeo (11.1%) groups. CP was predominantly ipsilesional (85.7%) in the pGeo group. Follow-up caloric tests indicated decreased CP in 72.7% of pGeo patients, with normalization in 36.4% following the disappearance of nystagmus.
conclusionThe clinical course, caloric tests, and vHIT.
resultsindicate distinct pathophysiological mechanisms for different LSCC BPPV types. Cupular deflection due to buoyancy in pGeo DCPN plausibly leads to CP while preserving vHIT integrity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.