Evidence map›Paper›PMID 40223376›Full record

ArticleOrthopaedic surgery2025

Comparison of Clinical Outcomes Between Primary and Salvage Reverse Shoulder Arthroplasty for Proximal Humeral Fractures: A Retrospective Study.

Qing Zhang, Sujan Shakya, Yi Cao, Ming Xiang, Zhou Xiang, Xin Duan

Abstract readComparative Study
In one paragraph

Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Qing ZhangDepartment of Orthopedic Surgery, School of Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-3943-3511
Sujan ShakyaDepartment of Orthopedic Surgery, School of Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-0243-0843
Yi CaoAffiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ming XiangDepartment of Upper Limb, Sichuan Provincial Orthpaedics Hospital, Chengdu, China.
Zhou XiangDepartment of Orthopedic Surgery, School of Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-1470-5805
Xin DuanDepartment of Orthopedic Surgery, School of Medicine, West China Hospital, Sichuan University, Chengdu, China.

Funding

National Natural Science Foundation of China 82202705Sichuan Provincial Care Health Research Project 2023-401The Project of the Science and Technology Department of Sichuan Province 2022YFS0099
6 · The paper itself

Abstract

objectiveThis study provides a comparative analysis of clinical outcomes between primary and salvage reverse shoulder arthroplasty (RSA), offering valuable insights into the management of proximal humerus fracture (PHF). To evaluate the outcomes of patients treated with RSA as a primary procedure for acute PHF and to compare these with patients undergoing salvage RSA as a revision procedure for fracture sequelae of PHF.

methodsA retrospective cohort study was conducted on 42 patients undergoing RSA for PHF between December 2014 and April 2022. The primary RSA group (n = 28, mean age 73.8 ± 4.5 years, 66-81 years) included patients with acute fractures, while the salvage RSA group (n = 14, mean age 62.1 ± 12.3 years, 47-83 years) comprised revision cases for fracture sequelae. Active range of motion (ROM), Visual Analog Scale (VAS), Constant score, and American Shoulder and Elbow Surgeons (ASES) scores were assessed for all patients. Outcomes between the two groups were compared, along with radiographic outcomes and complications recorded at each follow-up. Categorical variables were analyzed using chi-square or Fisher's exact tests, while continuous variables were compared using independent t-tests or Mann-Whitney U tests based on data distribution.

resultsAt a mean follow-up of 56 months (24-106 months), no significant differences in gender (p = 0.469) or follow-up duration (p = 0.087) were observed. The salvage group exhibited comparable postoperative ROM (anterior flexion (AF): 101.4° ± 52.3° vs. 115.9° ± 29.1°; external rotation (ER): 26.4° ± 16.4° vs. 28.8° ± 14.1°; internal rotation (IR): 7 ± 2 vs. 7 ± 2; all p > 0.05) and clinical scores (VAS: 1.6 ± 1.9 vs. 1.2 ± 1.5; Constant: 74.1 ± 23.3 vs. 79.4 ± 15.9; ASES: 81.9 ± 15.4 vs. 84.0 ± 13.8; all p > 0.05) to the primary group. However, the salvage group demonstrated significant preoperative-to-postoperative improvements in AF (50.9°, p < 0.001), ER (5.4, p = 0.017), and functional scores (VAS: -4.6; Constant: + 36.9; ASES: + 45.8; all p < 0.05). Complications occurred in 14.3% of salvage cases (2 revisions for periprosthetic fracture and aseptic loosening) versus 3.6% in the primary group. No other major complications such as deep infection, instability, acromial stress fracture, or dislocation were recorded.

conclusionRSA achieves comparable functional and radiographic outcomes for both acute PHF and fracture sequelae over 4 years of follow-up. Salvage RSA provides substantial clinical improvement but carries a higher complication risk, emphasizing the need for meticulous surgical technique and patient selection.

Indexed as

Arthroplasty, Replacement, ShoulderSalvage TherapyShoulder FracturesAgedAged, 80 and overFemaleHumansMaleMiddle AgedRange of Motion, ArticularReoperationRetrospective StudiesTreatment Outcomeclinical outcomesfailed osteosynthesisproximal humeral fracturereverse shoulder arthroplasty

Identifiers

PMID40223376
PMCPMC12146130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.