ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2025
Factors Affecting Continuation of Aripiprazole Long-acting Injection in the Real World.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Treatment continuation and factors associated with discontinuation with 3-month paliperidone palmitate in patients with schizophrenia: aFrontiers in psychiatry · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Aripiprazole long-acting injection (LAI) is both effective and widely used in clinical practice. Notably, no previous studies have examined the factors affecting the continuation of aripiprazole LAI within the Korean population. This study aims to identify real-world factors contributing to the continuation of aripiprazole LAI. Methods: A 1-year retrospective cohort study was conducted on 68 patients initiating aripiprazole LAI at Inha University Hospital, Korea. Patient medical records were reviewed to assess continuation rates, the duration from initiation to discontinuation, and reasons for discontinuation. Results: Overall, 27.9% of patients discontinued aripiprazole LAI within 12 months. The predominant reasons for discontinuation were insufficient efficacy (42.1%), adverse effects (31.6%), and preference for oral medication (21.1%). Univariate analysis revealed associations between discontinuation and patient compliance. After adjustment for sociodemographic factors, patient compliance and transitioning from paliperidone LAI to aripiprazole LAI were associated with the continuation of aripiprazole LAI. Multiple logistic regression analysis, adjusted for sociodemographic variables and compliance, identified significant associations between discontinuation and compliance. Conclusion: This study supports the clinical effectiveness of aripiprazole LAI, demonstrated by a reduced one-year discontinuation rate compared to that observed in a paliperidone LAI study with a similar design. Large-scale, long-term prospective studies are essential to definitively ascertain the factors associated with LAI discontinuation.
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