Evidence map›Paper›PMID 40223254›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2025

Autonomic Readiness for Social Threats in Patients with Social Anxiety Disorder.

Si Woo Kim, Dasom Lee, Jae Hyun Kim, Joongsuk Lee, Deung Hyun Kang, So-Yeon Kim, Soo-Hee Choi

Abstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Occupational Stress in the Neuroticism-Burnout Link: An Exploratory Examination of Physiological Contributions.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Si Woo KimDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0009-0003-1249-0414
Dasom LeeDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-3776-2263
Jae Hyun KimDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-1108-8162
Joongsuk LeeDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-3596-6089
Deung Hyun KangDepartment of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0009-0008-6485-9638
So-Yeon KimDepartment of Psychology, Duksung Women's University, Seoul, Korea.ORCID https://orcid.org/0000-0002-3219-9654
Soo-Hee ChoiDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-4507-6108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Pathological anxiety is characterized by dysregulated arousal and lower heart rate variability associated with emotional dysregulation. This study explored the connection between peripheral and central autonomic nervous system activity during emotional processing in social anxiety disorder (SAD). Methods: Thirty-two patients with SAD and 41 healthy controls engaged in a passive viewing task alternating between neutral and angry faces. The root mean square of successive differences (RMSSD) was measured during the resting state (baseline RMSSD) and emotional processing (task RMSSD). We examined the relationships between brain activation during emotional processing and these RMSSD measures. Results: Unlike the controls, the SAD group exhibited a trend level toward significant correlations of baseline RMSSD with left anterior insula activity during neutral face processing ( Conclusion: This study delineates distinct autonomic and neural response patterns to emotional stimuli in SAD patients, highlighting increased autonomic readiness and diminished flexibility in response to social threats.

Indexed as

Autonomic readinessPeripheral and central autonomic nervous systemSocial anxiety disorder

Identifiers

PMID40223254
PMCPMC12000662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.