Evidence map›Paper›PMID 40223047›Full record

ArticleBMC oral health2025

Materials and effects of intraoral device technologies for complication protection in head and neck cancer radiotherapy: a scoping review.

Luiza Simões Pires da Silva Figueiredo, Everton Granemann Souza, Chiara das Dores do Nascimento, Giovane Hisse Gomes, Rafael Guerra Lund, Evandro Piva

Abstract readScoping Review
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luiza Simões Pires da Silva FigueiredoUndergraduate Program in Dentistry, Catholic University of Pelotas, Pelotas, RS, 96015, Brazil.
Everton Granemann SouzaGraduate Program in Electronic and Computer Engineering, Catholic University of Pelotas, Pelotas, RS, 96015-560, Brazil.
Chiara das Dores do NascimentoGraduate Program in Electronic and Computer Engineering, Catholic University of Pelotas, Pelotas, RS, 96015-560, Brazil.
Giovane Hisse GomesUndergraduate Program in Dentistry, Catholic University of Pelotas, Pelotas, RS, 96015, Brazil.
Rafael Guerra LundGraduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, RS, 96010-560, Brazil. rafael.lund@gmail.com.
Evandro PivaGraduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, RS, 96010-560, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico DT-1D: 306225/2021-2Secretaria de Inovação, Ciência e Tecnologia do State of Rio Grande do Sul - Techfuturo Saúde 06/2023 SICT 20/2023, FPE Number: 3704/2023
6 · The paper itself

Abstract

backgroundThis review aims to analyze the effectiveness of intraoral devices, emphasizing predominant materials, key manufacturing technologies, and their prophylactic role in mitigating complications during radiotherapy for head and neck cancer patients.

methodsThe searches were conducted in the PubMed, ScienceDirect, Medline, VHL, Cochrane Library, SciELO, INCA, and MedRxiv databases using the MeSH descriptors "radiation therapy," "intraoral devices," and "protection." These descriptors were connected by the Boolean operator "AND," with a focus on articles published up to 2024. The study, carried out by two independent reviewers following the PRISMA checklist, focused on analyzing intraoral radiation protection devices. It explores the materials used in their fabrication, beam type, dose, and irradiation techniques employed during radiotherapy sessions. Additionally, the study investigates the side effects associated with and without the use of these devices in patients.

resultsEvidence emphasizes the specific dental needs of head and neck cancer patients. Furthermore, the hypothesis regarding the benefits of these devices in reducing setup errors and minimizing toxic doses to healthy tissues during radiotherapy is supported. These devices are composed of different materials, with varying densities and designs tailored to their intended function. 3D printing proves to be an effective tendency in the manufacturing of these instruments.

conclusionThese findings indicate a positive impact of using these devices for functional preservation, improvement in quality of life, and a reduction in the demand for oral treatments and rehabilitation. The analysis underscores the importance of determining the applicability for each clinical case of the specific radiotherapeutic treatment.

Indexed as

Head and Neck NeoplasmsMouth ProtectorsRadiation InjuriesRadiation ProtectionRadiotherapyEquipment DesignHumansHead and neck cancerIntraoral devicesOral radiation protectionRadiation therapy

Identifiers

PMID40223047
PMCPMC11995484

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.