Evidence map›Paper›PMID 40223030›Full record

ArticleScientific reports2025

Concentration-dependent disturbances of digestive functions in house cricket (Insecta: Orthoptera) exposed to GO-AgNP composite.

Reyhaneh Seyed Alian, Barbara Flasz, Andrzej Kędziorski, Magdalena Rost-Roszkowska, Katarzyna Rozpędek, Łukasz Majchrzycki, Maria Augustyniak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reyhaneh Seyed AlianInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland.
Barbara FlaszInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland.
Andrzej KędziorskiInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland.
Magdalena Rost-RoszkowskaInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland.
Katarzyna RozpędekInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland.
Łukasz MajchrzyckiInstitute of Physics, Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, Piotrowo 3, 60-965, Poznan, Poland.
Maria AugustyniakInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007, Katowice, Poland. maria.augustyniak@us.edu.pl.

Funding

Narodowe Centrum Nauki UMO-2021/41/N/NZ7/01974Research Excellence Initiative of the University of Silesia in Katowice POB5
6 · The paper itself

Abstract

This study investigates the effects of graphene oxide (GO) and silver nanoparticle (AgNP) composite (GO-AgNP) on the digestive physiology and gut ultrastructure of Acheta domesticus (house cricket) during extended exposure. Various concentrations of GO-AgNP were tested to assess their impact on food consumption, assimilation, cell status (Dead Cells and ROS + cells), gut enzyme activity, and structural damage to gut cells. Concentration and exposure time had significant effects on oxidative stress, enzyme activity, and gut cell structure. The applied composite reduced cumulative food consumption and assimilation efficiency. Enzyme assays showed that lower concentrations enhanced carbohydrate-degrading enzyme activity, while higher concentrations inhibited protease activity. Histological analysis revealed structural damage to gut epithelial cells and signs of autophagy or necrosis at higher concentrations. These results suggest that GO and AgNPs contribute to oxidative stress, cell cycle disruption, and apoptosis, with AgNPs having a potentially stronger effect than GO. The disturbed enzyme activity may result from conformational changes caused by nanoparticle agglomeration. These findings underline potential risks associated with the environmental or agricultural use of GO-AgNP composites.

Indexed as

DigestionGraphiteGryllidaeMetal NanoparticlesSilverAnimalsApoptosisGastrointestinal TractOxidative StressReactive Oxygen Speciesgraphene oxideGraphiteReactive Oxygen SpeciesSilverAcheta domesticusDead cells and ROS + cellsDigestive enzymesFood consumption and assimilationGut histology

Identifiers

PMID40223030
PMCPMC11994775

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.