ArticleAnnals of hematology2025
Association between radiotherapy and overall survival or cancer-specific survival in patients with solitary plasmacytoma of bone at pre-B cell grade: a real-world study using the SEER database.
Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Solitary plasmacytoma of the tibia: literature review and case report.Frontiers in oncology · 2026Article
- Solitary Plasmacytoma of the Rib: A Report of a Rare Case.The American journal of case reports · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limited real-world studies have compared radiation therapy (RT) to non-RT for patients with solitary plasmacytoma of bone (SPB). This study investigated the impact of RT on long-term survival outcomes in patients with SPB at the pre-B cell grade within a real-world context. We conducted a retrospective cohort analysis using data from the Surveillance, Epidemiology, and End Results (SEER) database for patients diagnosed with SPB at the pre-B cell grade between 2010 and 2017. Patients were categorized into two groups based on receipt of RT. We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) to investigate the value of RT for overall survival (OS) and cancer-specific survival (CSS). Survival curves were generated using the Kaplan-Meier method. A total of 1,922 individuals with SPB at the pre-B cell grade met the inclusion and exclusion criteria. Among these, 1,417 (74%) received RT, while 505 (26%) underwent non-RT. Multivariate Cox regression analysis revealed higher rates of OS (HR = 0.64, 95% CI = 0.55-0.74, p < 0.0001) and CSS (HR = 0.68, 95% CI = 0.56-0.82, p < 0.0001) in patients who received RT. These results remained consistent across sensitivity and subgroup analyses. Analysis of the SEER database suggests that RT is associated with improved OS and CSS and is the primary treatment for patients with SPB at the pre-B cell grade.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.