Evidence map›Paper›PMID 40222932›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Intravenous Methylprednisolone for Acute Right Middle Cerebral Artery Occlusion in Granulomatosis Polyangiitis.

Tsubasa Watanabe, Nakako Tanaka-Mabuchi, Yuto Morishima, Takanori Hata, Ryosuke Ito, Sho Nakajima, Atsuhiko Shindo, Yuki Nakamura, Hideyuki Yoshioka, Koji Hashimoto and 4 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tsubasa WatanabeDepartment of Neurology, University of Yamanashi, Japan.
Nakako Tanaka-MabuchiDepartment of Rheumatology, University of Yamanashi, Japan.
Yuto MorishimaDepartment of Neurology, University of Yamanashi, Japan.
Takanori HataDepartment of Neurology, University of Yamanashi, Japan.
Ryosuke ItoDepartment of Rheumatology, University of Yamanashi, Japan.
Sho NakajimaDepartment of Neurology, University of Yamanashi, Japan.
Atsuhiko ShindoDepartment of Neurology, University of Yamanashi, Japan.
Yuki NakamuraDepartment of Neurology, University of Yamanashi, Japan.
Hideyuki YoshiokaDepartment of Neurosurgery, University of Yamanashi, Japan.
Koji HashimotoDepartment of Neurosurgery, University of Yamanashi, Japan.
Kazumasa ShindoDepartment of Neurology, University of Yamanashi, Japan.
Hiroyuki KinouchiDepartment of Neurosurgery, University of Yamanashi, Japan.
Daiki NakagomiDepartment of Rheumatology, University of Yamanashi, Japan.
Yuji UenoDepartment of Neurology, University of Yamanashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 17-year-old Japanese woman diagnosed with granulomatosis with polyangiitis (GPA) and was treated with immunotherapy suddenly developed an impaired consciousness, left hemiplegia, and conjugate eye deviation to the right. Magnetic resonance imaging showed an acute cerebral infarction in the right striatum and right middle cerebral artery (MCA) occlusion. As her GPA had worsened recently, intravenous methylprednisolone (IVMP) was started. Immediately after IVMP was started, recanalization of the MCA was detected on repeat cerebral angiography. Aspirin and argatroban dissolved the residual thrombi. A combination of IVMP and antithrombotic therapy may be effective for large-vessel occlusions associated with GPA.

Indexed as

Granulomatosis with PolyangiitisInfarction, Middle Cerebral ArteryMethylprednisoloneAcute DiseaseAdministration, IntravenousAdolescentFemaleHumansTreatment OutcomeMethylprednisolonecerebral infarctiongranulomatosis polyangiitismiddle cerebral artery occlusionvasculitis

Identifiers

PMID40222932
PMCPMC12589154

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.