Evidence map›Paper›PMID 40222926›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Disseminated Fusariosis Successfully Treated with Empirical Liposomal Amphotericin B and Voriconazole Combination Followed by Ocular Therapy in an Allogenic Hematopoietic Stem Cell Transplant Recipient.

Yuya Kishida, Masahiro Sakaguchi, Tomoyuki Kunishige, Atsushi Takeyoshi, Taichiro Tokura, Kazuki Inai, Ryosuke Kinoshita, Toshio Ibaraki, Satoshi Yamanaka, Toshio Asayama and 3 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Infection and drug resistance · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuya KishidaDepartment of Hematology, Nippon Medical School, Japan.
Masahiro SakaguchiDepartment of Hematology, Nippon Medical School, Japan.
Tomoyuki KunishigeDepartment of Ophthalmology, Nippon Medical School, Japan.
Atsushi TakeyoshiDepartment of Hematology, Nippon Medical School, Japan.
Taichiro TokuraDepartment of Hematology, Nippon Medical School, Japan.
Kazuki InaiDepartment of Hematology, Nippon Medical School, Japan.
Ryosuke KinoshitaDepartment of Hematology, Nippon Medical School, Japan.
Toshio IbarakiDepartment of Hematology, Nippon Medical School, Japan.
Satoshi YamanakaDepartment of Hematology, Nippon Medical School, Japan.
Toshio AsayamaDepartment of Hematology, Nippon Medical School, Japan.
Shunsuke YuiDepartment of Hematology, Nippon Medical School, Japan.
Satoshi WakitaDepartment of Hematology, Nippon Medical School, Japan.
Hiroki YamaguchiDepartment of Hematology, Nippon Medical School, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 61-year-old man with chronic myelomonocytic leukemia, who underwent unrelated peripheral blood stem cell transplantation. Fusariosis was suspected prior to identification of the fungal species, and voriconazole and liposomal amphotericin B combination therapy were administered. The patient developed fusarium-related endophthalmitis, accompanied by eye pain. Despite vitrectomy, the endophthalmitis was poorly controlled, and the left eye was enucleated. No recurrence of fusariosis was observed until death following multiple-organ failure due to steroid-resistant graft-versus-host disease.

Indexed as

Amphotericin BAntifungal AgentsEndophthalmitisFusariosisHematopoietic Stem Cell TransplantationDrug Therapy, CombinationHumansMaleMiddle AgedTransplantation, HomologousVoriconazoleAmphotericin BAntifungal Agentsliposomal amphotericin BVoriconazoleallogeneic hematopoietic stem cell transplantationeye enucleationfusariosisliposomal amphotericin Bvoriconazole combination therapy

Identifiers

PMID40222926
PMCPMC12549048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.