Evidence map›Paper›PMID 40221966›Full record

ArticleJournal of Parkinson's disease2025

Pregnancy and delivery in women with Parkinson's disease: A case series.

Willanka M Kapelle, Annelien M Oosterbaan, Gaia Patane, Capucine Piat, Khaled E Ghoniem, Emanuele Camerucci, Pierpaolo Turcano, James H Bower, Rodolfo Savica

Abstract read
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. About pregnancy in Parkinson's disease.Journal of Parkinson's disease · 2026
    Article
  2. Sex and gender-related differences in neurological diseases: current challenges and recommendations for clinical practice.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Willanka M KapelleDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-1998-740X
Annelien M OosterbaanDepartment of Neurology, Radboudumc, Nijmegen, The Netherlands.ORCID 0000-0002-6543-4972
Gaia PataneNeurology, Università di Bologna, Bologna, Italy.
Capucine PiatDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Khaled E GhoniemAlzheimer's Disease Research Center, Mayo Clinic, Rochester, MN, USA.
Emanuele CamerucciDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Pierpaolo TurcanoDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-3240-8348
James H BowerDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Rodolfo SavicaDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-2543-0627

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundParkinson's disease (PD) is a progressive degenerative disease affecting people at any age; however, it is generally more prevalent in older age groups. Younger individuals, especially women, are facing significant challenges that pertain to pregnancy. Unfortunately, the available information is limited and supported mostly by anecdotical experience.ObjectiveTo gain insight into the interaction between early-onset PD and pregnancy.MethodsWe report on a case series of women, diagnosed with PD, that underwent pregnancy to explore the disease catachrestic, natural history, and different challenges associated with these unique group of people.ResultsWe identified a total of 9 participants who met our inclusion criteria, who had gone through a total of 12 pregnancies after onset of PD motor symptoms. In 10 out of 12 pregnancies, participants did not use any PD medication; throughout 1 pregnancy, a participant used pramipexole and throughout 1 pregnancy, a participant used levodopa/carbidopa.ConclusionsOur study supports the importance of further multicentric studies on pregnant women with PD to prospectively collect data on complications, birth outcomes, lactation, and PD severity.

Indexed as

Antiparkinson AgentsParkinson DiseasePregnancy ComplicationsAdultCarbidopaDrug CombinationsFemaleHumansLevodopaPregnancyPregnancy OutcomeAntiparkinson AgentsCarbidopacarbidopa, levodopa drug combinationDrug CombinationsLevodopagender medicineParkinson's diseasepregnancy

Identifiers

PMID40221966
PMCPMC13347462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.