Evidence map›Paper›PMID 40221912›Full record

ReviewKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

The projected economic burden and complications of revision hip and knee arthroplasties: Insights from national registry studies.

Patrick Sadoghi, Amir Koutp, Daniel Perez Prieto, Martin Clauss, M Enes Kayaalp, Michael T Hirschmann

Abstract readReview
In one paragraph

Review in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Narrative over numbers: How testimonial medicine erodes safe practice.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Article
  2. Epidemiology and healthcare burden of implant-associated complications in Germany: a nationwide population-based analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Enhancing Bone Healing with a Priming Stimulus.Life (Basel, Switzerland) · 2026
    Article
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  5. Review
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  8. Perioperative denosumab exposure and risk of revision after total hip and knee arthroplasty in osteoarthritis: a registry-based data linkage study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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  17. The projected economic burden and complications of revision hip and knee arthroplasties: Insights from national registry studies.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrick SadoghiDepartment of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0003-1767-555X
Amir KoutpDepartment of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-5992-4708
Daniel Perez PrietoOrthopedic Department, Septic Unit, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain.
Martin ClaussDepartment for Orthopaedics and Trauma Surgery, University Hospital Basel, Basel, Switzerland.
M Enes KayaalpDepartment of Orthopaedics and Traumatology, University of Health Sciences, Istanbul Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Michael T HirschmannDepartment of Orthopedic Surgery and Traumatology, Kantonsspital Baselland, Bruderholz, Binningen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising volume of primary hip and knee arthroplasties has led to a parallel increase in revision surgeries, creating significant clinical and economic challenges for healthcare systems worldwide. This study synthesizes national arthroplasty registry data to evaluate trends in revision aetiology, associated costs and regional disparities. While advancements in prosthetic design have reduced aseptic loosening rates (declining to 35.1% for hips and 18.3% for knees), septic complications now account for a growing proportion of revision cases, rising to 18.2% for hips and 21.6% for knees. Additionally, instability and malalignment persist at 15.9% and 14.1%, respectively. Revision procedures are 76% more costly than primary surgeries, with two-stage septic revisions incurring costs of up to $37,297 per case. Beyond direct surgical costs, prolonged recovery and productivity loss contribute to a broader economic impact. Regional variations, such as higher periprosthetic fracture rates in England and Wales, highlight inconsistencies in data reporting and healthcare practices. Addressing these challenges requires standardized infection definitions, enhanced registry collaboration and investment in infection prevention strategies. The role of referral centres in improving outcomes and reducing costs through multidisciplinary care is increasingly recognized. By integrating evidence-based infection management protocols and leveraging emerging technologies, the orthopaedic community can optimize patient outcomes and reduce the financial burden of revising arthroplasties. LEVEL OF EVIDENCE: Level IV.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeCost of IllnessPostoperative ComplicationsReoperationHealth Care CostsHumansProsthesis FailureProsthesis-Related InfectionsRegistriesaseptic looseninghip arthroplastyknee arthroplastynational registryseptic complications

Identifiers

PMID40221912
PMCPMC12392383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.