Evidence map›Paper›PMID 40221778›Full record

ArticleHarm reduction journal2025

Drug use and harm reduction practices of applicants to a public health vending machine service in Clark County, NV, 2021-2023.

Rachel Q Bryant, Kathleen Reich, Jessica A Johnson, Brandon Delise, Ying Zhang, Cassius Lockett, Sean T Allen

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachel Q BryantSouthern Nevada Health District, 280 S. Decatur Blvd, Las Vegas, NV, 89107, USA. rqbryant@gmail.com.
Kathleen ReichImpact Exchange, Las Vegas, NV, USA.
Jessica A JohnsonSouthern Nevada Health District, 280 S. Decatur Blvd, Las Vegas, NV, 89107, USA.
Brandon DeliseSouthern Nevada Health District, 280 S. Decatur Blvd, Las Vegas, NV, 89107, USA.
Ying ZhangSouthern Nevada Health District, 280 S. Decatur Blvd, Las Vegas, NV, 89107, USA.
Cassius LockettSouthern Nevada Health District, 280 S. Decatur Blvd, Las Vegas, NV, 89107, USA.
Sean T AllenJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

Bloomberg American Health Initiative NA
6 · The paper itself

Abstract

backgroundIn 2017, Clark County, NV, implemented Public Health Vending Machines (PHVMs), an innovative approach to the dispensation of harm reduction supplies to persons who inject drugs (PWID), including sterile equipment and naloxone. Administrative data associated with PHVM operations can be valuable for understanding drug use behaviors among PWID. The current study examines the demographics and drug use profiles of PHVM registrants who completed the harm reduction survey between January 2021 to June 2023 with comparison to nation-wide trends.

methodsAll registration forms for PHVM services in Clark County, NV, between 1/1/2021-6/30/2022 with a completed harm reduction survey were included for analysis. Descriptive statistics were used to characterize differences in applicant demographics as well as self-reported injection and non-injection drug use, risk behaviors, and interest in harm reduction services. Logistic regression models tested the association between types of injection drug use and overdose and risk behaviors.

resultsA total of 637 PHVM applications with completed survey data were included for analysis. Respondents were an average of 36.1 ± 10.2 years old, 56.3% male sex, and 63.6% non-Hispanic White with 85.1% reporting injection drug use (IDU). Notably, greater proportions of respondents with histories of IDU also indicated non-injection drug administration, such as smoking and snorting. In the 3 months prior to registration, the majority of IDU respondents reported high risk drug use behaviors, including daily use, multiple injections per day, and opioid and stimulant co-use. Fentanyl was suspected in 62.1% of overdoses in the last 3 months. Compared to PWID using stimulants only, respondents with opioid and stimulant co-use had a higher likelihood of overdose (aOR 4.51; 95% CI 2.05, 11.1; p < 0.001) and re-using injection supplies (aOR 2.14; 95% CI 1.33, 3.48; p = 0.002). More opioid and stimulant co-use respondents were interested in treatment/detox and obtaining naloxone than those without co-use.

conclusionsThe demographics and drug use behaviors of the PHVM PWID are consistent with contemporaneous county and nation-wide. As the overdose crisis evolves, PHVM could be pivotal tools in the early detection of new risks to facilitate timely adaptation of harm reduction strategies to improve morbidity and mortality.

Indexed as

Harm ReductionSubstance Abuse, IntravenousAdultDrug OverdoseFemaleHumansMaleMiddle AgedNaloxoneNeedle-Exchange ProgramsPublic HealthRisk-TakingYoung AdultNaloxoneHarm reductionInjection drug useNaloxoneOpioidOverdosePublic health vending machinesStimulant

Identifiers

PMID40221778
PMCPMC11992778

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.