Evidence map›Paper›PMID 40221758›Full record

ArticleBiomedical engineering online2025

Exploration of the effect of morphology and location on hemodynamics of small aneurysms: a variable-controlled study based on two cases with tandem aneurysms.

Jun Wan, Yeqing Jiang, Ligang Xu, Qimin Zhang, Guanghu Xu, Long Yu, Xinzhuo Li, Xiaolong Zhang, Shengzhang Wang

Erratum issuedAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jun Wan *Academy for Engineering and Technology, Fudan University, Shanghai, China.
Yeqing JiangDepartment of Radiology, Huashan Hospital Affiliated to Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Ligang XuDepartment of Interventional Radiology, Jing'an District Central Hospital, Fudan University, Shanghai, 200040, China.
Qimin ZhangDepartment of Aeronautics and Astronautics, Institute of Biomechanics, Fudan University, No. 220 Handan Road, Shanghai, 200433, China.
Guanghu XuDepartment of Aeronautics and Astronautics, Institute of Biomechanics, Fudan University, No. 220 Handan Road, Shanghai, 200433, China.
Long YuDepartment of Aeronautics and Astronautics, Institute of Biomechanics, Fudan University, No. 220 Handan Road, Shanghai, 200433, China.
Xinzhuo LiDepartment of Aeronautics and Astronautics, Institute of Biomechanics, Fudan University, No. 220 Handan Road, Shanghai, 200433, China.
Xiaolong ZhangDepartment of Radiology, Huashan Hospital Affiliated to Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China. xiaolongzhang@fudan.edu.cn.
Shengzhang WangAcademy for Engineering and Technology, Fudan University, Shanghai, China. szwang@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmall aneurysms are usually treated with a flow diverter alone, without coils. However, some continue to exhibit incomplete occlusion after treatment, even after an extended period. This study aimed to investigate the effects of aneurysm morphology and location on the hemodynamic parameters related to poor outcomes.

methodsTwo patients with tandem aneurysms were enrolled. Flow diverter deployment was simulated, and preoperative and postoperative hemodynamics were analyzed using computational fluid dynamics. The preoperative and postoperative hemodynamics of the actual surgical plan were simulated using finite element analysis and computational fluid dynamics. The correlation between morphology, hemodynamics, and incomplete occlusion was evaluated by calculating the hemodynamics of aneurysm models with different heights and neck widths, adjusted according to the original geometry.

resultsSimulation of the actual surgical plan showed that the incompletely occluded aneurysm had a larger postoperative velocity at the sac and neck region (v

conclusionAneurysms located on the superior wall of the internal carotid artery ophthalmic segment or with a larger neck or height present a more severe hemodynamic environment, requiring careful consideration when planning surgery. This study provides hemodynamic evidence demonstrating how morphology affects aneurysm progression.

Indexed as

HemodynamicsIntracranial AneurysmAgedFemaleFinite Element AnalysisHumansHydrodynamicsMaleMiddle AgedComputational fluid dynamicsComputed fluid dynamicFlow diverter deviceTandem aneurysmsTubridge

Identifiers

PMID40221758
PMCPMC11992751

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