Evidence map›Paper›PMID 40221677›Full record

ArticleBMC surgery2025

Long-term outcomes of ventriculoperitoneal shunt therapy in idiopathic normal pressure hydrocephalus.

Jingyu Chen, Jishu Xian, Feilong Wang, Chenghai Zuo, Li We, Zhi Chen, Rong Hu, Hua Feng

Abstract read
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jingyu Chen *Department of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China. cjy1_2001@hotmail.com.
Jishu Xian *Department of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Feilong WangDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Chenghai ZuoDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Li WeDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Zhi ChenDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Rong HuDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.
Hua FengDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, 400038, P. R. China.

Funding

Chongqing Medical Scientific Research Project 2020FYYX201
6 · The paper itself

Abstract

backgroundLimited data are available regarding the long-term functional outcomes and associated factors in patients with idiopathic normal pressure hydrocephalus (iNPH) undergoing ventriculoperitoneal shunt (VPS) placement. This study aimed to retrospectively evaluate the long-term outcomes of iNPH patients treated with VPS.

methodsFunctional outcomes were assessed preoperatively and at 1-year, 2-year, and 3-year intervals postoperatively using the modified Rankin Scale (mRS), the iNPH grading scale (iNPHGS), and the Mini-Mental State Examination (MMSE).

resultsSignificant improvements were observed in mRS and iNPHGS scores at 1, 2, and 3 years post-surgery compared to the baseline level. MMSE scores showed significant improvement at 1-year and 3-year follow-ups. Multivariate regression analysis identified key factors influencing changes in mRS scores: postoperative complications and education level at 1 year, postoperative complications at 2 years, and sex, education level, postoperative complications, and smoking at 3 years. For iNPHGS scores, significant factors included sex, age at surgery, and smoking at 1 and 2 years. Changes in MMSE scores were associated with sex and the duration of preoperative symptoms at 1 year, and postoperative complications, education level, and smoking at 3 years.

conclusionThis study affirmed the efficacy and safety of VPS in managing iNPH. Factors influencing postoperative outcomes predominantly included education level, smoking, duration of preoperative symptoms, and postoperative complications. However, further research is required to validate these findings.

Indexed as

Hydrocephalus, Normal PressureVentriculoperitoneal ShuntAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTime FactorsTreatment OutcomeFollow-upFunctional outcomeIdiopathic normal pressure hydrocephalusVentriculoperitoneal shunt

Identifiers

PMID40221677
PMCPMC11992790

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.