Evidence map›Paper›PMID 40221641›Full record

Trial reportBMC anesthesiology2025

Comparison of the incidence and severity of postoperative sore throat and subglottic airway injury with cylindrical versus tapered cuff endotracheal tubes in women undergoing surgery for breast cancer: a randomized controlled trial.

Geng-Ci Chen, Kai-Li Lo, Zhi-Fu Wu, Shun-Ming Chan, Sheng-Yao Cheng, Ching-Lung Ko, Chi-Ming Chu, Wei-Cheng Tseng

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06505850 (Comparisons of Postoperative Sore Throat and Subglottic Airway Injury Between Endotracheal Tubes With Different Cuff Shapes in Breast Cancer Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06505850 nacompletednot on this map

Comparisons of Postoperative Sore Throat and Subglottic Airway Injury Between Endotracheal Tubes With Different Cuff Shapes in Breast Cancer Patients

TypeinterventionalSponsorTri-Service General Hospital (TSGH)Ran2024 to 2025Enrolled176ConditionsBreast Cancer, Postoperative Sore Throat, Subglottic Airway Injury, Endotracheal Tube CuffArmsTapered-shaped cuff tracheal tube, Cylindrical-shaped cuff tracheal tube
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Geng-Ci ChenDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Kai-Li LoDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Zhi-Fu WuDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Shun-Ming ChanDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Sheng-Yao ChengDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei City, Taiwan.
Ching-Lung KoDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Chi-Ming ChuGraduate Institute of Life Sciences, National Defense Medical Center, Taipei City, Taiwan.
Wei-Cheng TsengDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan. ndmc_wechern@yahoo.com.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative sore throat (POST) is a minor complication of general anesthesia with tracheal intubation but may negatively affect patient satisfaction and postoperative recovery. The shape of the endotracheal tube (ETT) cuff may influence the incidence and severity of POST.

methodsThis prospective, randomized, double-blinded study was conducted on 174 female patients with breast cancer. They were randomized into the cylindrical (CYL) (group C) and tapered (TAP) (group T) cuff ETT groups. Data on patient demographics, surgical characteristics, and factors related to tracheal intubation were collected. Furthermore, the incidence and severity of POST at the selected time points were duly recorded for analysis. Other adverse events and anesthesia satisfaction were also documented.

resultsDuring the 48-h evaluation period, group T exhibited reduced overall incidence of POST compared with group C. The incidence and severity of POST at 1, 6, 12, 24, and 48 h postoperatively were also significantly lower in group T than in group C. No significant difference in subglottic airway injury was observed between the two groups. Postoperative anesthesia satisfaction was higher in group T.

conclusionsThe present study demonstrates that the utilization of a TAP cuff ETT rather than a CYL cuff ETT in patients undergoing breast cancer surgery reduced the incidence and severity of POST. The selection of an appropriate ETT for surgical patients could play a pivotal role in alleviating airway complications, enhancing postoperative recovery, and improving anesthesia satisfaction.

trial registrationThe study was registered at ClinicalTrials.gov (NCT06505850) on 2024-07-17.

Indexed as

Breast NeoplasmsIntubation, IntratrachealPharyngitisPostoperative ComplicationsAdultAgedAnesthesia, GeneralDouble-Blind MethodEquipment DesignFemaleHumansIncidenceMiddle AgedPatient SatisfactionProspective StudiesSeverity of Illness IndexBreast cancerEndotracheal tube cuffPostoperative sore throatSubglottic airway injuryTracheal intubation

Identifiers

PMID40221641
PMCPMC11992810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.