Evidence map›Paper›PMID 40221629›Full record

ArticleScientific reports2025

Initial experience with the novel modular robotic system Carina in urology: a prospective study on safety feasibility and surgical settings.

Gaurab Pokhrel, ZeYuan Wang, Jinshan Cui, Bingzhai Jin, Haoke Zheng, Jin Tao, Yafeng Fan, Yunlong Liu, Yonghao Zhan, Shuanbao Yu and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07632638 (Safety and Technical Evaluation of a Robotic Platform), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07632638 narecruitingnot on this mapstarted 2026, after this paper: background citation

Safety and Technical Evaluation of a Robotic Platform (RonovoTM) in Elective Oncological Surgery: A Prospective, Single-Arm, Multi-Specialty Registry

TypeinterventionalSponsorInstituto do Cancer do Estado de São PauloRan2026 to 2026Enrolled40ConditionsMalignant Neoplasms, CancerArmsRonovoTM Robotic Surgical Platform
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. [Evaluation of the feasibility and safety of a Chinese developed modular surgical robotic system for robot-assisted pyeloplasty].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gaurab PokhrelDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
ZeYuan WangDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Jinshan CuiDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Bingzhai JinDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Haoke ZhengDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Jin TaoDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Yafeng FanDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Yunlong LiuDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Yonghao ZhanDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Shuanbao YuDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Biao DongDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Xuepei ZhangDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. zhangxuepei@263.net.

Funding

Next Generation of Surgical Imaging and Robotics for Supervised Autonomous Soft Tissue SurgeryR01EB020610 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI HSIEH, MICHAEL HARRISON, KANG, JIN U · 2016 to 2019
$1.5M
Development and Pre-Clinical Evaluation of a Robotic System for Supervised Autonomous Tumor SurgeryR21EB024707 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI KRIEGER, AXEL · 2017 to 2018
$446k
National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health 1R01EB020610, and R21EB024707Natural Science Foundation of Henan 222300420344NIBIB NIH HHS R01 EB020610NIBIB NIH HHS R21 EB024707
6 · The paper itself

Abstract

Robot-assisted surgery has transformed urology, but widespread adoption remains limited by the high cost, complex setup, and rigid system design. This prospective single-center study evaluates the safety and efficacy of the novel modular Carina in 19 upper and lower urinary tract surgeries. All cases were completed robotically without conversion, with one major complication. For partial nephrectomy (PN), median operative time (OT) was 120 min with 50 mL estimated blood loss (EBL), including one off-clamp PN completed in 77 min (EBL: 50 mL). Pyeloplasty had a median OT of 105 min (EBL: 50 mL), while radical prostatectomy (RP) achieved a median OT of 150 min (EBL: 50 mL). Radical cystectomy was completed in 301 min without major complications, and an uncomplicated postoperative course. Median docking times were 5 and 8 min for upper and lower tract surgeries, with negative margins and preserved renal function in all PN, and social continence post-RP. The Carina system demonstrates procedural safety and feasibility in complex urological procedures. The modular design may enhance workflow and space utilization, suggesting the potential for promising tool and broader clinical applications. Further validation with larger sample sizes and long-term follow-up is needed.

Indexed as

Robotic Surgical ProceduresUrologic Surgical ProceduresAdultAgedCystectomyFeasibility StudiesFemaleHumansMaleMiddle AgedNephrectomyOperative TimeProspective StudiesProstatectomyCarina™ platformModular systemNovel robotic systemRobot assisted surgerySurgical settingsUrologic proceduresUrology

Identifiers

PMID40221629
PMCPMC11993754

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.