Evidence map›Paper›PMID 40221614›Full record

ArticleMolecular diversity2026

Novel 2-aminothiazole derivatives incorporating 9-alkyl purine moiety: design, synthesis, crystal structure, and bioactivity evaluation.

Song Bai, Suran Wan, Miao Li, Rong Wu, Shouying Tang, Fang Wang, Lijun Chen, Xiaokang Lv, Xian Wei, Shuang Feng and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Song BaiGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China. basonmail@163.com.
Suran WanGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China. wansuran1213@163.com.
Miao LiGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Rong WuGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Shouying TangGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Fang WangGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Lijun ChenGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Xiaokang LvGuizhou Industry Polytechnic College, Guiyang, 550008, People's Republic of China.
Xian WeiSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, 550003, People's Republic of China.
Shuang FengSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, 550003, People's Republic of China.
Miaohe ZhangSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, 550003, People's Republic of China.

Funding

Basic Research Project of Guizhou Province Qian Ke He Ji Chu zk [2025]Mian Shang 003Guizhou Industry Polytechnic College Faculty-level Research Project 2023ZK10Guizhou Industry Polytechnic College Faculty-level Research Project 2023ZK11Guizhou Industry Polytechnic College Science and Technology Innovation Team Project 2023CXTD03Guizhou Provincial Department of Education Youth Science and Technology Talent Growth Project Qian Jiao Ji [2024]292 HaoGuizhou Provincial Department of Education Youth Science and Technology Talent Growth Project Qian Jiao Ji [2024]293 HaoHigh-Level Talent Initial Funding of Guizhou Industry Polytechnic College 2023-RC-01High School Science and Technology Talent Support Project of Guizhou Province, China Qian Jiao He KY Zi [2021]037Science and Technology Planning Project of Guizhou Province Qian Ke He Ji Chu ZK [2022]Zhong Dian 025the academic new seedling cultivation and exploration and innovation project of Guizhou Institute of Technology GZLGXM-20The Opening Foundation of the Key Laboratory of Green Pesticide and Agricultural Bioengineering, the Ministry of Education, Guizhou University Qian Jiao Ji [2022]433Young Science and Technology Talents Development Program of Education Department of Guizhou Province Qian Jiao He KY Zi [2022]346 Hao
6 · The paper itself

Abstract

A series of 2-aminothiazole derivatives (3A1-3A30) containing 9-alkyl purine moiety were designed and synthesized to explore novel antibacterial agents with unique structures and potent antibacterial activity. The structures of target compounds were characterized using

Indexed as

Anti-Bacterial AgentsDrug DesignPurinesThiazolesCrystallography, X-RayMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipXanthomonas2-aminothiazoleAnti-Bacterial AgentspurinePurinesThiazoles2-Aminothiazole derivatives9-Alkyl purineAntibacterial mechanismsAntimicrobial activityCrystal structure

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.