Evidence map›Paper›PMID 40221334›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2025

Balancing strength and translucency: The role of microstructure in additive and subtractive dental zirconia.

Mirelle M Ruggiero, Chek Hai Lim, Thomas S Giugliano, Mijin Choi, Altair A Del Bel Cury, Yu Zhang

Abstract read
In one paragraph

Article in Dental materials : official publication of the Academy of Dental Materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Translucency of 3D-Printed 3Y- and 5Y-Doped Zirconia.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  2. A Review of Current Systems, Materials, and Protocols for 3D-Printed Splints, Crowns, and Dentures.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mirelle M RuggieroSchool of Dental Medicine, University of Pennsylvania, 240 S. 40th St., Philadelphia, PA 19104, USA; University of Campinas, Piracicaba Dental School, Av. Limeira, 901, Piracicaba, SP 13414-903, Brazil. Electronic address: mirelleruggiero@gmail.com.
Chek Hai LimSchool of Dental Medicine, University of Pennsylvania, 240 S. 40th St., Philadelphia, PA 19104, USA. Electronic address: chekhai@upenn.edu.
Thomas S GiuglianoNew York University College of Dentistry, 345 E 24th St., New York, NY 10010, USA. Electronic address: tsg2@nyu.edu.
Mijin ChoiNew York University College of Dentistry, 345 E 24th St., New York, NY 10010, USA. Electronic address: mc185@nyu.edu.
Altair A Del Bel CuryUniversity of Campinas, Piracicaba Dental School, Av. Limeira, 901, Piracicaba, SP 13414-903, Brazil. Electronic address: altair@unicamp.br.
Yu ZhangSchool of Dental Medicine, University of Pennsylvania, 240 S. 40th St., Philadelphia, PA 19104, USA. Electronic address: yz21@upenn.edu.

Funding

Viscoelastic Modeling Aided Experimental Optimization toward Fracture-Resistant Porcelain-Veneered Zirconia and Lithium Disilicate RestorationsR01DE026279 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI KIM, JEONGHO, ZHANG, YU · 2017 to 2021
$2.0M
Toward novel translucent and strong nanostructured dental zirconiaR01DE026772 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI ZHANG, YU · 2017 to 2021
$1.8M
Ultrafast sintering of dental zirconia: composition-processing-property relationships with high-throughput fail-fast screeningR01DE033545 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Liangbing Hu, Yu Zhang · 2023 to 2026
$1.8M
NIDCR NIH HHS R01 DE026279NIDCR NIH HHS R01 DE026772NIDCR NIH HHS R01 DE033545
6 · The paper itself

Abstract

objectivesTo elucidate the effect of microstructure on the strength and translucency of dental zirconia fabricated using additive (AM) and subtractive manufacturing (SM) technologies.

methodsTwelve 3Y-TZP discs were fabricated using AM with two print orientations (0°: group AM0; 90°: group AM90; n = 6), and six via CAD/CAM machining (group SM). Density, composition, roughness, translucency parameter (TP), and biaxial flexural strength (σ) were evaluated. Fractographic analysis was conducted and defect size estimated. Based on the preliminary σ results (n = 6), the optimal print orientation was identified. Nine additional specimens were prepared for each of the AM90 and SM groups for Weibull σ analysis (n = 15). Differences in Weibull modulus were assessed via non-overlapping 95 % confidence intervals. An one-way ANOVA followed by Tukey's post-hoc test and an independent samples t-test were used (α = 0.05).

resultsThe relative density was consistent across all groups (>99 %). The tetragonal and cubic phases were comparable among groups, with proportions exceeding 82 wt% and 17 wt%, respectively. Group SM exhibited significantly higher roughness (1.18 µm) than AM0 (0.71 µm) and AM90 (0.51 µm). Group SM exhibited the highest TP values, while groups AM0 and AM90 had statistically similar TP values. AM0 showed the lowest σ value (411.60 ± 73.99 MPa) and larger defects. Groups AM90 and SM (n = 15) possessed comparable σ values (969.85 ± 123.13 MPa and 989.72 ± 107.78 MPa, respectively) (p = 0.6417) and Weibull moduli (9.17 and 10.62, respectively). SIGNIFICANCE: SM zirconia showed higher translucency and roughness, while defects reduced translucency in AM zirconia. Flexural strength was lower for AM0 due to larger defects, whereas AM90 matched SM strength.

Indexed as

Dental MaterialsYttriumZirconiumComputer-Aided DesignDental Stress AnalysisFlexural StrengthMaterials TestingSurface PropertiesDental MaterialsYttriumZirconiumzirconium oxide3D-printed zirconia3Y-TZPBuild orientationMicrostructureMilled zirconiaStrengthTranslucency

Identifiers

PMID40221334
PMCPMC12208504

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.