Evidence map›Paper›PMID 40221115›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2025

Ultrafine particles and late-life cognitive function: Influence of stationary mobile monitoring design on health inferences.

Magali N Blanco, Adam A Szpiro, Paul K Crane, Lianne Sheppard

Abstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Magali N BlancoDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA. Electronic address: magali@uw.edu.
Adam A SzpiroDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Paul K CraneDepartment of Medicine, University of Washington, Seattle, WA, USA.
Lianne SheppardDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA; Department of Biostatistics, University of Washington, Seattle, WA, USA.

Funding

Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Pamela A Shaw · 2021 to 2026
$80.4M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI SUMAN JAYADEV · 2020 to 2026
$29.0M
Air Pollution, the Aging Brain and Alzheimer's DiseaseR01ES026187 · NIEHS · UNIVERSITY OF WASHINGTON · PI LI, GAIL, SHEPPARD, ELIZABETH A LIANNE · 2016 to 2020
$3.8M
NIA NIH HHS P30 AG066509NIA NIH HHS U19 AG066567NIEHS NIH HHS R01 ES026187
6 · The paper itself

Abstract

Growing evidence links ultrafine particles (UFP) to neurotoxicity, but human studies remain limited. Various mobile monitoring approaches have been used to develop air pollution exposure models. However, whether design choices impact epidemiology, including for UFP and cognitive function, remains unclear. We evaluated the adjusted association between 5-year average UFP number concentration (PNC) and late-life cognitive function (Cognitive Abilities Screening Instrument - Item Response Theory [CASI-IRT]) in the Adult Changes in Thought cohort (N = 5283) by leveraging an extensive roadside mobile monitoring campaign specifically designed for epidemiology. To assess the impact of reduced monitoring approaches on this association, we repeatedly subsampled UFP measures from the campaign, developed exposure models, and evaluated the degree to which associations were impacted. In the primary analysis, each 1900 pt/cm

Indexed as

Air PollutantsAir PollutionCognitionEnvironmental ExposureEnvironmental MonitoringParticulate MatterAgedFemaleHumansMaleMiddle AgedParticle SizeAir PollutantsParticulate MatterAir pollutionEpidemiologyExposure assessmentLate-life cognitive functionMobile monitoring designUltrafine particles (UFP)

Identifiers

PMID40221115
PMCPMC12050196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.