Evidence map›Paper›PMID 40221004›Full record

SynthesisAmerican journal of preventive medicine2025

Effectiveness of School Fluoride Delivery Programs: A Community Guide Systematic Review.

Susan O Griffin, Mei Lin, Christina R Scherrer, Shillpa Naavaal, David P Hopkins, Anita A Jones, Tammy Alexander, Virginia A Black, Elizabeth Clark, Lori K Cofano and 8 more

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Susan O GriffinDivision of Oral Health, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: sig1@cdc.gov.
Mei LinDivision of Oral Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Christina R ScherrerDepartment of Systems and Industrial Engineering, Kennesaw State University, Kennesaw, Georgia.
Shillpa NaavaalPediatric Dentistry and Dental Public Health, Virginia Commonwealth University, Richmond, Virginia.
David P HopkinsCommunity Guide Program, Office of Science, CDC, Atlanta, Georgia.
Anita A JonesNational Institute for Occupational Safety and Health, CDC, Atlanta, Georgia.
Tammy AlexanderSchool-Based Health Alliance, Washington, District of Columbia.
Virginia A BlackNational Association of School Nurses, Silver Spring, Maryland.
Elizabeth ClarkNational Association of School Nurses, Silver Spring, Maryland.
Lori K CofanoAssociation of State and Territorial Dental Directors, Reno, Nevada.
Raul I GarciaDepartment of Health Policy & Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts.
Anna GoddardChild & Family Agency, New London, Connecticut.
Jane GroverAmerican Dental Association, Chicago, Illinois.
Susan M KansagraNorth Carolina Division of Public Health, Raleigh, North Carolina.
Thomas E KottkeHealth Partners Institute, Minneapolis, Minnesota.
Elizabeth C LenseAmerican Dental Association, Chicago, Illinois.
Tooka ZokaieSchool of Public Health, University of Illinois Chicago, Chicago, Illinois.
Community Preventive Services Task Force

Funding

Workflow Optimization for School-based Preventive Oral Health Services DeliveryR15DE031428 · NIDCR · KENNESAW STATE UNIVERSITY · PI Christina Scherrer · 2022 to 2026
$1.1M
Intramural CDC HHS CC999999NIDCR NIH HHS R15 DE031428
6 · The paper itself

Abstract

introductionAlthough preventable, dental caries remains highly prevalent. Many children do not receive preventive dental services routinely in clinical settings. This review examined the effectiveness of school (preschool through high school) fluoride varnish delivery programs in preventing caries.

methodsCommunity Guide systematic review methods were followed. In 2024, databases were searched for studies published through December 2023 on school flouride varnish delivery program effectiveness in increasing fluoride varnish receipt and decreasing caries. Included studies had to be written in English, published in peer-reviewed journals, and conducted in upper-middle- or high-income countries. Data synthesis conducted in 2024 used median RR and interquartile interval (IQI) to summarize findings across studies.

resultsOf 31 included studies with 60,780 students, 25 were randomized controlled trials-20 with good quality of execution. Most studies were conducted in low socioeconomic status areas among students at elevated caries risk. School flouride varnish delivery programs reduced caries initiation by 32% (IQI: 21%, 37%) in permanent teeth (19 studies, 25,826 students) and by 25% (IQI: 4%, 37%) in primary teeth (12 studies, 4,304 students). Stratified assessments indicated findings were largely applicable to different settings, populations, and intervention characteristics. Two studies found school flouride varnish delivery programs significantly increased the number of annual flouride varnish applications and 2 found that school flouride varnish delivery program effectiveness was inversely related to socioeconomic status. DISCUSSION: About 30% of states report having no school flouride varnish delivery programs. Possible barriers to implementation include that Medicaid in some states only reimburses dental and medical professionals and does not reimburse non-dental providers for flouride varnish delivered to children older than age 6 years.

Indexed as

Cariostatic AgentsDental CariesFluorides, TopicalSchool Health ServicesAdolescentChildChild, PreschoolHumansRandomized Controlled Trials as TopicSchoolsCariostatic AgentsFluorides, Topical

Identifiers

PMID40221004
PMCPMC12185235

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.