ArticleAnnals of epidemiology2025
Drug overdose mortality rates among non-Hispanic American Indian/Alaska Native individuals, 1999-2022.
Article in Annals of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Recent incarceration and minoritized racial status as barriers to the effectiveness of recovery management checkups.Substance abuse treatment, prevention, and policy · 2025Trial
- Commentary on Friedman et al.: Inequitable improvements and data gaps-A call for better drug surveillance data.Addiction (Abingdon, England) · 2026Article
- Over-the-counter naloxone sales and pricing variability in North Carolina following FDA approval.Journal of substance use and addiction treatment · 2026Article
- Higher drug overdose mortality among non-hispanic black adults aged 55 and older in the U.S.: Analysis of national death records from CDC's WONDER database (1999-2023).Drug and alcohol dependence reports · 2026Article
- Patterns of polysubstance use among people who use drugs on an American Indian reservation of a southern plains Tribal Nation.Harm reduction journal · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposeTo examine epidemiological trends in drug overdose deaths for non-Hispanic American Indian/Alaska Native (AIAN) individuals compared to White individuals.
methodsWe obtained data from the CDC WONDER database to examine crude drug overdose death rates per 100,000 among AIAN and White individuals from 1999-2022. Rates were further stratified by manner of death, sex, age, urbanization, Census region, state, and specific drug types.
resultsFrom 1999-2022, drug overdose death rates for AIAN individuals increased from 3.17 (95 % CI, 2.48-4.00) to 40.73 (95 % CI, 38.19-43.27), representing a 12-fold increase; in contrast, rates rose by five-fold for White individuals. In 2022, methamphetamine was the leading driver of overdose death rates for AIAN individuals, at 31.39 (95 % CI, 29.16-33.62) per 100,000, followed by fentanyl, at 22.35 (95 % CI, 20.46-24.23) per 100,000. Geographical variations were notable, with the highest rates for AIAN individuals in large central metropolitan regions (53.54 per 100,000) and the Midwest (50.31 per 100,000). Rates were higher for AIAN than White individuals in 20 of the 21 states (95.2 %) included in our analysis.
conclusionsAIAN individuals are disproportionately impacted by the overdose crisis. Further efforts are needed to expand access to harm reduction-informed, culturally-competent health education, addiction treatment, and social services in the AIAN population.
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