ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2025
Accelerated real-time cine and flow under in-magnet staged exercise.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- EMORe: Motion-Robust 5D MRI Reconstruction via Expectation-Maximization-Guided Binning Correction and Outlier Rejection.IEEE transactions on medical imaging · 2026Article
- Exercise MRI stress testing of the human heart at 3 Tesla: measurement precision of biventricular function and aortic blood flow during steady-state bicycling exercise.Magma (New York, N.Y.) · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundCardiovascular magnetic resonance (CMR) imaging is a well-established imaging tool for diagnosing and managing cardiac conditions. The integration of exercise stress with CMR (ExCMR) can enhance its diagnostic capacity. Despite recent advances in CMR technology, quantitative ExCMR during exercise remains technically challenging due to motion artifacts and limited spatial and temporal resolution.
methodsThis study investigated the feasibility of biventricular functional and hemodynamic assessment using real-time (RT) ExCMR during a staged exercise protocol in 24 healthy volunteers. We employed high acceleration rates and applied a coil-reweighting technique to minimize motion blurring and artifacts. We further applied a beat-selection technique that identified beats from the end-expiratory phase to minimize the impact of respiration-induced through-plane motion on cardiac function quantification. Additionally, results from six patients were presented to demonstrate clinical feasibility.
resultsOur findings indicated a consistent decrease in end-systolic volume and stable end-diastolic volume across exercise intensities, leading to increased stroke volume and ejection fraction. The selection of end-expiratory beats modestly enhanced the repeatability of cardiac function parameters, as shown by scan-rescan tests in nine volunteers. High scores from a blinded image quality assessment indicated that coil reweighting effectively minimized motion artifacts.
conclusionThis study demonstrated the feasibility of RT ExCMR with in-magnet exercise in healthy subjects and patients. Our results indicate that high acceleration rates, coil reweighting, and selection of respiratory phase-specific heartbeats enhance image quality and repeatability of quantitative RT ExCMR.
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