Evidence map›Paper›PMID 40220329›Full record

Trial reportPsycho-oncology2025

Symptom Attribution, Help Seeking and Willingness to Undergo Diagnostic Investigations for Bowel Cancer Symptoms in People With Anxiety and/or Depression-A Vignette Study.

Bettina Friedrich, Cristina Renzi, Lucy Mitchinson, Rupert A Payne, Samuel W D Merriel, Georgios Lyratzopoulos, Gary Abel, Christian von Wagner

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bettina FriedrichResearch Department of Behavioural Science and Health, University College London, London, UK.
Cristina RenziResearch Department of Behavioural Science and Health, University College London, London, UK.
Lucy MitchinsonCentre for Prevention, Detection and Diagnosis, Queen Mary University of London, London, UK.
Rupert A PayneHealth and Community Sciences, University of Exeter, Exeter, UK.
Samuel W D MerrielCentre for Primary Care and Health Services Research, University of Manchester, Manchester, UK.ORCID 0000-0003-2919-9087
Georgios LyratzopoulosResearch Department of Behavioural Science and Health, University College London, London, UK.
Gary AbelHealth and Community Sciences, University of Exeter, Exeter, UK.
Christian von WagnerResearch Department of Behavioural Science and Health, University College London, London, UK.

Funding

National Institute for Health and Care Research
6 · The paper itself

Abstract

backgroundBowel cancer is a common cause of cancer deaths and survival increases dramatically with earlier diagnosis. People with mental health problems such as anxiety and/or depression (A/D) are less likely to engage in health behaviours important for early detection.

aimsWe explored whether three processes crucial for early cancer diagnosis are different in the A/D group compared to controls: (1) 'attributions' that is, assumed causes of bodily changes typical for bowel cancer, (2) help seeking actions participants would be likely to take and (3) willingness to do a relevant test (stool test or sigmoidoscopy/colonoscopy).

methodsIn this randomised online vignette study, 1883 participants were presented one of four scenarios that each featured one bodily change typical of bowel cancer. Attributions were indicated using a free text response option. Help seeking options were presented in a list and likelihood of engaging in them was explored. Willingness to take a test was assessed using a question with response options 'yes', 'no' and 'unsure'.

resultsParticipants with A/D were more likely to attribute symptoms to their mental health than to cancer. Male participants with A/D were less likely to engage in several help-seeking actions. Participants in the A/D group were less likely to be willing to undergo invasive diagnostic testing.

conclusionsPeople with A/D should be encouraged to take bodily changes typical of cancer seriously and be proactive in help seeking and taking tests. Clinicians need to be aware that people with A/D may misattribute bodily changes associated with cancer and support them to seek help and undergo testing.

Indexed as

AnxietyColorectal NeoplasmsDepressionHelp-Seeking BehaviorPatient Acceptance of Health CareAdultAgedColonoscopyEarly Detection of CancerFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedSigmoidoscopyattributionbowel cancercancercomorbiditydiagnostic testearly detectionhealth psychologyhelp seekingmental healthoncology

Identifiers

PMID40220329
PMCPMC11993246

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.