Evidence map›Paper›PMID 40220236›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Analysis of TF/DNA Binding in T Cells Applying Alpha Technology.

Nikolaus Thuille, Gottfried Baier

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nikolaus ThuilleDepartment for Genetics, Medical University of Innsbruck, Institute for Cell Genetics, Innsbruck, Austria.
Gottfried BaierDepartment for Genetics, Medical University of Innsbruck, Institute for Cell Genetics, Innsbruck, Austria. gottfried.baier@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bead-based luminescent Alpha technology is a fast, highly sensitive, and robust method for studying DNA-binding activities of the transcription factors NF-kappaB and AP-1 in human or murine T cells. It represents a reproducible and time-efficient technology, which can replace classical EMSA method and is thus an ideal tool in basic research for the study of cellular transcriptional regulatory responses.

Indexed as

DNALuminescent MeasurementsNF-kappa BT-LymphocytesTranscription Factor AP-1AnimalsHumansMiceProtein BindingDNANF-kappa BTranscription Factor AP-1Alpha technologyBead based luminescent assayT cell signallingTF/DNA binding

Identifiers

PMID40220236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.