Evidence map›Paper›PMID 40220213›Full record

Trial reportJournal of clinical monitoring and computing2025

Impact of cardiopulmonary bypass flow on the lower limit of cerebral autoregulation during cardiac surgery: a randomized cross-over pilot study.

Olivier Desebbe, Antoine Berna, Alexandre Joosten, Darren Raphael, Ghislain Malapert, Dimitri Rolo, Fabio Silvio Taccone, Laurent Gergele

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Olivier DesebbeDepartment of Anesthesiology and perioperative care, Ramsay Sante, Sauvegarde Clinic, Lyon, France. oldesebbe@yahoo.com.
Antoine BernaDepartment of Anesthesiology and perioperative care, Ramsay Sante, Sauvegarde Clinic, Lyon, France.
Alexandre JoostenDepartment of Anesthesiology & Perioperative Care, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Darren RaphaelDepartment of Anesthesiology & Perioperative Care, University of California Irvine, Irvine, CA, 92868, USA.
Ghislain MalapertDepartment of Cardiac Surgery, Ramsay Sante, Sauvegarde Clinic, Lyon, France.
Dimitri RoloDepartment of Anesthesiology and perioperative care, Ramsay Sante, Sauvegarde Clinic, Lyon, France.
Fabio Silvio TacconeDepartment of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles, Brussels, Belgium.
Laurent GergeleDepartment of Anesthesiology and Perioperative Care, Ramsay Sante, Hôpital Privé de la Loire, Saint-Etienne, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessment of cerebral autoregulation is challenging under different hemodynamic conditions during cardiac surgery and must be rapidly calculated in order to optimize mean arterial pressure (MAP). Whether systemic flow during cardiopulmonary bypass impacts the lower limit of cerebral autoregulation (LLA) remains unclear. Forty patients requiring cardiac surgery were included in this randomized crossover study. Patients assigned to the conventional/high blood flow arm received 20 min of conventional cardiopulmonary bypass (CPB) blood flow (2.2 L/min.m

Indexed as

Cardiac Surgical ProceduresCardiopulmonary BypassCerebrovascular CirculationHomeostasisAgedArterial PressureBlood Flow VelocityCross-Over StudiesFemaleHemodynamicsHumansMaleMiddle AgedMiddle Cerebral ArteryMonitoring, IntraoperativePilot ProjectsCardiopulmonary bypassCerebral autoregulationMean arterial pressurePump flow

Identifiers

PMID40220213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.