Evidence map›Paper›PMID 40220183›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Functional sinonasal outcomes after rescue flap versus double nasoseptal flap in endoscopic trans-sphenoid pituitary surgery: a randomized clinical trial.

Ahmad Muhammad Al-Arman, Waleed Moneir, Hazem Emam Amer, Mahmoud Saad, Hisham Atef Ebada

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Ahmad Muhammad Al-ArmanDepartment of Otorhinolaryngology, Mansoura University, Mansoura, 35511, Egypt.
Waleed MoneirDepartment of Otorhinolaryngology, Mansoura University, Mansoura, 35511, Egypt.
Hazem Emam AmerDepartment of Otorhinolaryngology, Mansoura University, Mansoura, 35511, Egypt.
Mahmoud SaadDepartment of Neurosurgery, Mansoura University, Mansoura, Egypt.
Hisham Atef EbadaDepartment of Otorhinolaryngology, Mansoura University, Mansoura, 35511, Egypt. hishamebada@mans.edu.eg.ORCID http://orcid.org/0000-0003-4848-9223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the current study was to evaluate the functional sinonasal outcomes after rescue flap versus double nasoseptal flap in endoscopic endonasal pituitary surgery.

methodsThis randomized clinical trial was conducted over 1.5 years over 60 patients who underwent endoscopic trans-sphenoid surgery for macroadenomas (more than 2 cm.). the patients were randomly allocated into 2 groups: the rescue flap group, (n = 30) and the double nasoseptal flap group (n = 30). Functional sinonasal outcomes were evaluated in both groups in terms of sinonasal outcome test (SNOT-22), crusting, adhesions, and olfaction.

resultsthe sinonasal outcome test (SNOT-22), as well as the olfaction scores were significantly better in the double flap group compared to the rescue flap group. Crusting and adhesions occurred more frequently in the rescue flap group. The nasal stage operative time was significantly longer in the double flap group than the rescue flap group.

conclusionEndoscopic pituitary surgery can adversely affect the sinonasal functions. Double nasoseptal flap technique allows posterior septectomy with bilateral septal mucosa preservation. Although it requires longer operative time than the rescue flap technique, better functional sinonasal outcomes and olfaction scores are achieved.

Indexed as

AdenomaEndoscopyNasal SeptumPituitary NeoplasmsSurgical FlapsAdultAgedFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsSino-Nasal Outcome TestSmellTreatment OutcomeNasoseptal flapOutcomesPituitary adenomaRescue flapSinonasalTrans-sphenoid

Identifiers

PMID40220183
PMCPMC12055946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.