Evidence map›Paper›PMID 40220115›Full record

ArticleAnatomical science international2026

A rare variant of double origin of the left vertebral artery.

George Triantafyllou, Panagiotis Papadopoulos-Manolarakis, Fabrice Duparc, George Tsakotos, Maria Piagkou

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In one paragraph

Article in Anatomical science international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

George TriantafyllouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Goudi, 11527, Athens, Greece. georgerose406@gmail.com.ORCID http://orcid.org/0009-0001-0122-2436
Panagiotis Papadopoulos-ManolarakisDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Goudi, 11527, Athens, Greece.ORCID http://orcid.org/0009-0008-5662-8354
Fabrice DuparcDepartment of Anatomy, Faculty of Medicine-Pharmacy, University of Rouen-Normandy, Rouen, France.ORCID http://orcid.org/0000-0002-7131-7692
George TsakotosDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Goudi, 11527, Athens, Greece.ORCID http://orcid.org/0000-0001-8559-8969
Maria PiagkouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Goudi, 11527, Athens, Greece.ORCID http://orcid.org/0000-0002-4831-8005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vertebral artery (VA) demonstrates considerable variability, including infrequent morphologic variants like double origin. The current imaging report presents an atypical case of a dual origin of a left vertebral artery (LVA), which was identified incidentally during routine computed tomography angiography of a 51-year-old male patient. The typical LVA originated from the left subclavian artery (LSCA), and the other one was an aberrant LVA (ALVA) that arose from the aortic arch (AA) in between the left common carotid artery (LCCA) and the LSCA. The two vessels (LVA and ALVA) converged proximally to the transverse process of the C6 vertebra. The embryological explanation for this variant likely pertains to the persistence of primitive dorsal aortic segments and intersegmental arteries. Although rare, with a prevalence of 0.1%, the occurrence of LVA double origin may have significant clinical implications, including alterations in hemodynamics, an increased risk of VA dissection, and complications during surgical or endovascular procedures. The identification of such variants through preoperative imaging is essential to prevent iatrogenic complications.

Indexed as

Anatomic VariationAorta, ThoracicSubclavian ArteryVertebral ArteryCarotid Artery, CommonComputed Tomography AngiographyHumansIncidental FindingsMaleMiddle AgedAnatomyAortic archDouble originVariationVertebral artery

Identifiers

PMID40220115
PMCPMC12987874

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