Evidence map›Paper›PMID 40220053›Full record

Trial reportInternational urogynecology journal2025

Effect of Preoperative Tamsulosin on Postoperative Urinary Retention Prevention After Sling Placement: A Randomized Controlled Trial.

Angela Leffelman, Henry Chill, Claudia Paya-Ten, Alireza Hadizadeh, Jungeun Lee, Cecilia Chang, Ghazaleh Rostaminia

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela LeffelmanDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA. angela.leffelman@gmail.com.
Henry ChillDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA.
Claudia Paya-TenDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA.
Alireza HadizadehDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA.
Jungeun LeeNorthshore University Healthsystem Research Institute, Evanston, IL, USA.
Cecilia ChangDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA.
Ghazaleh RostaminiaDivision of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University Healthsystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe objective of this study was to evaluate whether preoperative administration of tamsulosin would decrease the frequency of postoperative urinary retention (POUR) after mid-urethral sling (MUS) placement

methodsThis was a prospective randomized, double-blinded, placebo-controlled trial of patients with SUI who underwent elective MUS placement at a single institution. Patients scheduled to undergo MUS placement consented, were enrolled, and were randomized to receive either a single tablet of tamsulosin 0.4 mg or placebo in the preoperative holding area on the day of their surgery. We then evaluated the rate of POUR after administration of tamsulosin compared with placebo using appropriate statistical methods. Sample size was calculated to include 160 patients.

resultsA total of 161 patients (81 placebo, 80 tamsulosin) were analyzed. The incidence of POUR was similar between the tamsulosin and placebo groups (17.7% vs 19.8%, p = 0.7420). Secondary outcomes, including unplanned admissions, urinary-tract infections (UTIs), and hypotension, did not differ significantly between groups. A subgroup analysis of patients undergoing MUS without concomitant prolapse surgery suggested a trend toward lower POUR rates in the tamsulosin group (7.5% vs 16.7%, p = 0.142), although this was not statistically significant.

conclusionThese results suggest that single-dose preoperative tamsulosin might not have an effect on postoperative urinary retention after MUS placement, with or without concomitant reconstructive pelvic surgery.

Indexed as

Adrenergic alpha-1 Receptor AntagonistsPostoperative ComplicationsSuburethral SlingsSulfonamidesUrinary Incontinence, StressUrinary RetentionAdultAgedDouble-Blind MethodFemaleHumansMiddle AgedPreoperative CareProspective StudiesTamsulosinAdrenergic alpha-1 Receptor AntagonistsSulfonamidesTamsulosinMid-urethral slingPostoperative urinary retentionTamsulosin

Identifiers

PMID40220053
PMCPMC12182465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.