Evidence map›Paper›PMID 40219842›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Sex Differences in Head and Neck Carcinoma - A Retrospective Study on 1115 Head and Neck Carcinoma Patients in Austria.

Barbara Kofler, Margarethe Hochleitner, Benedikt Hofauer, Wegene Borena, Daniel Dejaco, Volker Schartinger, Michelle Liu, Teresa Steinbichler, Jozsef Dudas, Matthias Santer and 2 more

Abstract read
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Sex influences on tumor innervation.Biology of sex differences · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Barbara KoflerDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-0102-455X
Margarethe HochleitnerGender Medicine Unit, Medical University of Innsbruck, Innsbruck, Austria.
Benedikt HofauerDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Wegene BorenaInstitute of Virology, Medical University of Innsbruck, Innsbruck, Austria.
Daniel DejacoDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Volker SchartingerDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Michelle LiuDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Teresa SteinbichlerDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Jozsef DudasDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Matthias SanterDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Joachim SchmutzhardDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Herbert RiechelmannDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ImportanceIn different types of carcinoma, sex has a strong impact on risk factors, diagnosis, treatment, and outcomes. Previous studies have reported that female patients with head and neck carcinoma (HNC) have better survival.ObjectiveThis study aimed to analyze sex differences in tumor regression and survival, as well as host- and disease-related factors.DesignA retrospective cohort study.SettingTertiary Care, University Hospital.Participants1115 patients registered in the Head and Neck Tumor Registry of the Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck were included.Main Outcome MeasuresSeveral host- and disease-related factors were analyzed to determine possible sex differences.ResultsThis study included 1115 patients with HNC, of whom 78.6% (n = 876) were men and 21.4% (n = 239) were women. There were no differences in tumor regression or incident cases per year in our department between male and female patients with HNC. Statistically significant sex differences were found for tumor site (

Indexed as

Head and Neck NeoplasmsAdultAgedAged, 80 and overAustriaFemaleHumansMaleMiddle AgedNeoplasm StagingRegistriesRetrospective StudiesRisk FactorsSex FactorsSurvival Ratefemale healthhead and neck cancerrisk factorssex differencesUICC stage

Identifiers

PMID40219842
PMCPMC12033396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.