Evidence map›Paper›PMID 40219613›Full record

ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2025

Induced Abortion After Previous Caesarean Section: A Scoping Review.

Natalie Drever, Vinay Gangathimmaiah, Brittany van Der Lugt, Cecelia O'Brien, Catriona Melville, Kirsten Black, Caroline de Costa

Abstract readScoping Review
In one paragraph

Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalie DreverCollege of Medicine and Dentistry, James Cook University, Cairns, Queensland, Australia.ORCID 0000-0003-3906-8769
Vinay GangathimmaiahCollege of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.
Brittany van Der LugtDepartment of Obstetrics and Gynaecology, Cairns Hospital, Cairns, Queensland, Australia.
Cecelia O'BrienCollege of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.
Catriona MelvilleDepartment of Obstetrics and Gynaecology, Logan Hospital, Metro South Hospital and Health Service, Meadowbrook, Queensland, Australia.
Kirsten BlackDepartment of Obstetrics, Gynaecology and Neonatology, School of Medicine, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-0030-2431
Caroline de CostaThe Cairns Institute, James Cook University, Cairns, Queensland, Australia.ORCID 0000-0002-4994-7196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious caesarean section (CS) is increasingly common among women undergoing induced abortion.

aimsTo map and analyse existing literature on abortion safety, outcomes and management in those with previous CS. MATERIALS AND

methodsFour databases were systematically searched from inception to July 2024. Primary human studies in English reporting on outcomes, safety or management of first- or second-trimester medical (MToP) or surgical (SToP) abortion in women with previous CS were included. Uterine rupture incidence was analysed cumulatively in the first and secondtrimesters by the number of CS and the type of prostaglandin used. Data on the efficacy and safety of MToP and SToP, including studies reporting on the management of abortion in the setting of abnormal placentation, were collected and analysed by theme.

resultsIn total, 164 articles met inclusion criteria. Incidence of uterine rupture in first-trimester MToP was 0 of 2194 cases, in second-trimester misoprostol MToP in those with 1 previous CS was 0.5% (10/1910) and 2.2% (18/835) in women with ≥ 2 CS (p < 0.001). Mifepristone priming did not increase the rupture rate in second-trimester MToP (p = 0.77). Previous CS was a modest risk factor for retained products after MToP across both trimesters (OR 1.48, CI 1.29-1.70).

conclusionMedical and surgical abortion in the first and second trimester appears safe in women with prior CS; however, risks include uterine rupture, need for surgical intervention and haemorrhage from undiagnosed placenta accreta. Further research and guidance are needed on managing abortion after previous classical CS, ≥ 3 previous CS and those with abnormally invasive placenta.

Indexed as

Abortion, InducedCesarean SectionUterine RuptureAbortifacient Agents, NonsteroidalFemaleHumansMifepristoneMisoprostolPregnancyPregnancy Trimester, FirstPregnancy Trimester, SecondAbortifacient Agents, NonsteroidalMifepristoneMisoprostolabortionaccretacaesarean sectionreviewtermination of pregnancy

Identifiers

PMID40219613
PMCPMC12723096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.