Evidence map›Paper›PMID 40219321›Full record

ArticlePolymers2025

Targeting Injectable Hydrogels: The Role of Diphenylalanine Peptide Derivative in the Gelation Dynamics of Pluronic

Vasile Robert Gradinaru, Maria Bercea, Luiza Madalina Gradinaru, Alexandru Puiu, Alexandra Lupu, Brindusa Alina Petre

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vasile Robert GradinaruFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Bd., 700506 Iasi, Romania.ORCID 0000-0001-5510-9730
Maria Bercea"Petru Poni" Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0003-0962-0372
Luiza Madalina Gradinaru"Petru Poni" Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0001-9106-8139
Alexandru PuiuFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Bd., 700506 Iasi, Romania.
Alexandra Lupu"Petru Poni" Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-0977-5414
Brindusa Alina PetreFaculty of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Bd., 700506 Iasi, Romania.ORCID 0000-0002-0208-6560

Funding

Executive Agency for Financing Higher Education, Research, Development and Innovation (UEFISCDI) from Romania project PN-III-P2-2.1-PED-2019-2484, contract no. 494 PED/2020
6 · The paper itself

Abstract

The fluorenyl methyl oxycarbonyl phenylalanyl-phenylalanine methyl ester (Fmoc-Phe-Phe-Ome) was synthetized using the liquid phase synthesis strategy. This derivative was separated by hydrophobic interaction chromatography, its purity was analyzed by RP-HPLC and it was characterized by mass spectrometry. This extremely hydrophobic peptide conjugate was incorporated into aqueous solutions of Pluronic

Indexed as

hydrophobic interactionsinjectable hydrogelpeptidePluronic® F127self-healingshear thinning

Identifiers

PMID40219321
PMCPMC11991411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.