Evidence map›Paper›PMID 40219274›Full record

ArticlePolymers2025

Sourcing Interchangeability in Commercial Chitosan: Focus on the Physical-Chemical Properties of Six Different Products and Their Impact on the Release of Antibacterial Agents.

Isabela Tavares Rampim, Helton José Wiggers, Cecilia Zorzi Bueno, Pascale Chevallier, Francesco Copes, Diego Mantovani

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabela Tavares RampimLaboratory for Biomaterials and Bioengineering (LBB-BPK), Associação de Ensino, Pesquisa e Extensão BIOPARK, Max Planck Avenue, 3797, Building Charles Darwin, Toledo 85919-899, PR, Brazil.
Helton José WiggersLaboratory for Biomaterials and Bioengineering (LBB-BPK), Associação de Ensino, Pesquisa e Extensão BIOPARK, Max Planck Avenue, 3797, Building Charles Darwin, Toledo 85919-899, PR, Brazil.ORCID 0000-0001-9531-6566
Cecilia Zorzi BuenoLaboratory for Biomaterials and Bioengineering (LBB-BPK), Associação de Ensino, Pesquisa e Extensão BIOPARK, Max Planck Avenue, 3797, Building Charles Darwin, Toledo 85919-899, PR, Brazil.ORCID 0000-0003-2365-5301
Pascale ChevallierLaboratory for Biomaterials and Bioengineering (LBB-UL), Department of Min-Met-Materials Engineering & CHU de Quebec Research Center, Division Regenerative Medicine, Laval University, Quebec City, QC G1V0A6, Canada.ORCID 0000-0002-0163-9936
Francesco CopesLaboratory for Biomaterials and Bioengineering (LBB-UL), Department of Min-Met-Materials Engineering & CHU de Quebec Research Center, Division Regenerative Medicine, Laval University, Quebec City, QC G1V0A6, Canada.ORCID 0000-0001-6901-971X
Diego MantovaniLaboratory for Biomaterials and Bioengineering (LBB-BPK), Associação de Ensino, Pesquisa e Extensão BIOPARK, Max Planck Avenue, 3797, Building Charles Darwin, Toledo 85919-899, PR, Brazil.ORCID 0000-0001-9672-895X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico CNPq 408919/2023-0Quebec Ministry of Economy and Innovation (under the hub of PRIMA, Quebec)
6 · The paper itself

Abstract

Sourcing and batch differences are often cited as intrinsic drawbacks for all natural polymers. Chitosan makes no exception. Chitosan is a biocompatible and biodegradable biopolymer with high potential for several biomedical applications, especially for releasing drugs and bactericidal and virucidal agents. Despite the potential of chitosan as a matrix for producing antibacterial films, the variability in its composition, stemming from its natural sources, can hinder the translation from bench to industry. To overcome this concern, we conducted a study to access the interchangeability of chitosan for the development of antibacterial drug release systems, in particular one system crosslinked with tannic acid and iron sulfate. Chitosans from different suppliers were characterized and used to synthetize films containing gentamicin, according to a previously reported protocol. The impact of molecular weight (M

Indexed as

chitosandrug release systemsinterchangeabilitynatural polymers

Identifiers

PMID40219274
PMCPMC11991257

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.