Biosynthesis and Its Regulatory Mechanisms of 2-(2-Phenylethyl)chromones in Agarwood.

Wenli Wu, Xiaoyang Jiang, Luyuan Jiang, Iain Wilson, Fenjuan Shao, Deyou Qiu

Abstract readReview

In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Unraveling the science of "sinking and dark-colored" superior agarwood through density, color, and metabolomics.RSC advances · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenli WuState Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.

Xiaoyang JiangState Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.

Luyuan JiangState Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.

Iain WilsonCSIRO Agriculture and Food, Canberra, ACT 2601, Australia.ORCID 0000-0002-4626-8059

Fenjuan ShaoState Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.ORCID 0000-0002-6279-0787

Deyou QiuState Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.

Funding

the Special Funds for Central Public-Interest Scientific Institution Public Welfare Projects CAFYBB2024MA021

6 · The paper itself

Abstract

Agarwood, a highly prized traditional medicinal material and natural spice, holds significant economic and medicinal value. Widely utilized as a fragrant agent, it is also employed in the treatment of diverse ailments, including rheumatism, fever, asthma, bronchitis, cancer, and gastrointestinal or reproductive disorders. These functions are primarily attributed to the accumulation of 2-(2-phenylethyl)chromones (PECs), a class of bioactive compounds. In recent years, PECs have emerged as critical components in the development of agarwood-derived pharmaceuticals and commercial products, garnering substantial scientific attention. This review consolidates current advancements in the structure and function of PECs and examines and discusses the structural genes and regulatory transcription factors associated with PECs biosynthesis. By synthesizing this knowledge, this review establishes a foundation for elucidating the complete biosynthetic pathways and regulatory mechanisms governing PECs production, thereby facilitating future research and applications.

Indexed as

2-(2-phenylethyl)chromonesbiosynthesis pathwayregulatory mechanismsstructure and function

Identifiers

PMID40219080

DOI10.3390/plants14071012

PMCPMC11990096

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.