Evidence map›Paper›PMID 40218421›Full record

ArticleAnimals : an open access journal from MDPI2025

Comparing Short

Konstantinos V Arsenopoulos, Eleni Michalopoulou, Elias Papadopoulos

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Konstantinos V ArsenopoulosDepartment of Veterinary Medicine, School of Veterinary Medicine, University of Nicosia, 2414 Nicosia, Cyprus.ORCID 0000-0002-6918-830X
Eleni MichalopoulouInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-2564-3267
Elias PapadopoulosLaboratory of Parasitology and Parasitic Diseases, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-2564-5203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGrazing dairy ewes are often heavily challenged by parasitic infections, which represent one of the most important concerns in sheep farming due to their impacts on dairy sheep production.

objectivesThe objectives of the present study were (i) to compare the short (i.e., albendazole) and long (i.e., eprinomectin) persistent effect of these anthelmintics in reducing infections by gastrointestinal nematodes (GIN) in ewes and (ii) to determine these effects on milk yield and quality in naturally infected with GIN dairy ewes.

methodsOn each farm, 40 selected ewes were divided into four similar groups on Day 0 based on their fecal egg counts (eggs per gram of feces; epg) as follows: Group 1-control group; Group 2-albendazole-treated group; Group 3-pour-on eprinomectin-treated group; Group 4-injectable eprinomectin-treated group. Fecal egg counts and coprocultures were performed on Days 0, 15, 30, 45, 60 and 75. The milk yield and milk quality (i.e., fat and protein concentration and somatic cell counts) were estimated on the aforementioned occasions.

resultsEprinomectin outperformed albendazole in treating gastrointestinal nematode infections in dairy ewes. Both pour-on and injectable eprinomectin formulations provided long-lasting protection by reducing fecal egg counts (i.e., from 92.1% to 99.9%). Furthermore, eprinomectin-treated ewes exhibited increased daily milk yield and improved milk composition in terms of fat and protein concentrations and somatic cell counts.

conclusionsThese findings highlight the benefits of long-persistent efficacy of eprinomectin as a preferred anthelmintic treatment for lactating dairy ewes, offering enhanced productivity and milk quality, while addressing parasite resistance concerns.

Indexed as

albendazoledairy eweseprinomectinfat and protein concentrationmilk yieldsomatic cell count

Identifiers

PMID40218421
PMCPMC11987907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.