Evidence map›Paper›PMID 40218414›Full record

ArticleAnimals : an open access journal from MDPI2025

Association of Stress and Inflammatory Diseases with Serum Ferritin and Iron Concentrations in Neonatal Calves.

Marlene Sickinger, Jessica Jörling, Kathrin Büttner, Joachim Roth, Axel Wehrend

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marlene SickingerClinic for Ruminants and Herd Health Management, Justus-Liebig-University of Giessen, 35392 Giessen, Germany.ORCID 0000-0002-2231-1622
Jessica JörlingVeterinary Practice Lünne, 48480 Lünne, Germany.
Kathrin BüttnerDepartment for Biomathematics and Data Processing, Justus-Liebig-University of Giessen, 35392 Giessen, Germany.
Joachim RothInstitute for Veterinary Physiology, Justus-Liebig-University of Giessen, 35390 Giessen, Germany.
Axel WehrendVeterinary Clinic for Reproduction and Neonatology, Justus-Liebig-University of Giessen, 35392 Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of iron supplementation and inflammatory disease on cortisol, white blood cell (WBC) count, total protein (TP), lactate, interleukin 1 β (IL1β), interleukin 6 (IL6), substance P (SP), hepcidin, haptoglobin, and ferric-reducing ability of plasma (FRAP) in calves. Correlation analyses for the aforementioned parameters with serum iron and ferritin were performed in 40 neonatal calves over the first 10 days of life. Neither iron supplementation, disease status, nor sex had statistically significant effects on the areas under the curve of ferritin, WBC, TP, IL1β, IL6, SP, hepcidin, haptoglobin, or FRAP. However, cortisol concentrations were influenced by disease development. Cortisol concentrations were higher at birth (44.1 ± 1.95 ng/mL) than on day 2 (38.8 ± 1.87 ng/mL) (

Indexed as

calfcortisolcytokineshaptoglobinhepcidininflammationiron supply

Identifiers

PMID40218414
PMCPMC11987952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.