Evidence map›Paper›PMID 40218406›Full record

ArticleAnimals : an open access journal from MDPI2025

Copeptin Hormone Concentrations in Dogs with Heart Disease and Relationship with Antidiuretic Hormone.

Corine Lavigne, Darcy B Adin, Courtney Hanner, Alexis Cooper, Rebeca A Castro, Autumn N Harris

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Corine LavigneDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA.
Darcy B AdinDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA.ORCID 0000-0003-0972-0365
Courtney HannerDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA.
Alexis CooperDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA.
Rebeca A CastroDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Dr, Raleigh, NC 27606, USA.ORCID 0000-0003-2770-3681
Autumn N HarrisDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA.ORCID 0000-0002-2329-3905

Funding

Maggy Spannuth Veterinary Cardiovascular Research Fund from the University of Florida Foundation NA
6 · The paper itself

Abstract

Antidiuretic hormone (ADH) is upregulated in dogs with cardiac disease. However, measurement of ADH is impractical in a clinical setting. Copeptin is co-secreted with ADH, making it a potential biomarker of ADH secretion. We hypothesized that dogs with cardiac disease would upregulate copeptin concentrations and that copeptin would positively correlate with ADH, serum chloride ([Cl

Indexed as

caninecardiovasculardiuretic resistancehypochloremia

Identifiers

PMID40218406
PMCPMC11988154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.