Evidence map›Paper›PMID 40218382›Full record

ReviewAnimals : an open access journal from MDPI2025

Towards Practical Conservation Cloning: Understanding the Dichotomy Between the Histories of Commercial and Conservation Cloning.

Ben J Novak, Stewart Brand, Ryan Phelan, Sasha Plichta, Oliver A Ryder, Robert J Wiese

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Biobanking biodiversity: recent strategies, challenges, and opportunities.The Journal of reproduction and development · 2026
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ben J NovakRevive & Restore, 1505 Bridgeway #203, Sausalito, CA 94965, USA.ORCID 0000-0003-0699-634X
Stewart BrandRevive & Restore, 1505 Bridgeway #203, Sausalito, CA 94965, USA.
Ryan PhelanRevive & Restore, 1505 Bridgeway #203, Sausalito, CA 94965, USA.
Sasha PlichtaDepartment of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Oliver A RyderBeckman Center for Conservation Research, San Diego Zoo Wildlife Alliance, Escondido, CA 92027, USA.ORCID 0000-0003-2427-763X
Robert J WieseNorth Carolina Museum of Natural Sciences, Raleigh, NC 27601, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over 40 years ago, scientists imagined ways cloning could aid conservation of threatened taxa. The cloning of Dolly the sheep from adult somatic cells in 1996 was the breakthrough that finally enabled the conservation potential of the technology. Until the 2020s, conservation cloning research efforts yielded no management applications, leading many to believe cloning is not yet an effective conservation tool. In strong contrast, domestic taxa are cloned routinely for scientific and commercial purposes. In this review, we sought to understand the reasons for these divergent trends. We scoured peer-reviewed and gray literature and sent direct inquiries to scientists to analyze a more comprehensive history of the field than was analyzed in previous reviews. While most previous reviewers concluded that a lack of reproductive knowledge of wildlife species has hindered advances for wider conservation applications, we found that resource limitations (e.g., numbers of surrogates, sustainable funding) and widely held misconceptions about cloning are significant contributors to the stagnation of the field. Recent successes in cloning programs for the endangered black-footed ferret (

Indexed as

black-footed ferretcloninggenetic rescuePrzewalski’s horsesomatic cell nuclear transfer

Identifiers

PMID40218382
PMCPMC11988126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.